HitPredict

Interactor 1: STK35 (Q8TDR2)
Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)
Gene: STK35

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 534 Hs			1 779
+	Hs
		566481 KPCA_HUMAN (17-532): 1.16e-118: 366: 15.47		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		408682 KPCB_HUMAN (17-530): 4.59e-114: 354: 15.34		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		625600 CDK2_HUMAN (199-533): 8.42e-115: 343: 22.86		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		331086 PAK4_HUMAN (36-526): 7.11e-102: 320: 21.86		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		850712 KS6A3_HUMAN (146-532): 1.13e-93: 303: 18.50		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1073480 KS6A1_HUMAN (154-532): 7.61e-91: 295: 18.93		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1317403 STK33_HUMAN (129-523): 2.74e-20: 95.9: 25.78		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1255349 STK35_HUMAN (1-523): 3.69e-130: 391: 100.00		OSBL3_HUMAN (52-563): 4.71e-44: 173: 11.36
+	Hs
		166612 DCLK1_HUMAN (150-448): 4.51e-17: 86.7: 28.95		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		566377 KPCA_HUMAN (17-532): 1.16e-118: 366: 15.47		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Mm
		930572 KPCG_MOUSE (17-532): 4.59e-112: 350: 15.04		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		408612 KPCB_HUMAN (17-530): 4.59e-114: 354: 15.34		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		625526 CDK2_HUMAN (199-533): 8.42e-115: 343: 22.86		CNKR2_HUMAN (1-468): 1.39e-46: 181: 13.77
+	Hs
		625495 CDK2_HUMAN (199-533): 8.42e-115: 343: 22.86		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		625491 CDK2_HUMAN (199-533): 8.42e-115: 343: 22.86		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1071703 KS6A2_HUMAN (182-532): 8.8e-94: 303: 20.11		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		166574 DCLK1_HUMAN (150-448): 4.51e-17: 86.7: 28.95		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		166557 DCLK1_HUMAN (150-448): 4.51e-17: 86.7: 28.95		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		166613 DCLK1_HUMAN (150-448): 4.51e-17: 86.7: 28.95		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		299256 CDK6_HUMAN (198-521): 1.7e-17: 85.5: 28.20		FARP2_HUMAN (5-183): 2.45e-30: 130: 21.69