HitPredict

Interactor 1: DLG5 (Q8TDM6)
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)
Gene: DLG5

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25900982, 31787846
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0008013 - beta-catenin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1919 Hs			1 605
+	Hs
		793015 DLG5_HUMAN (1-1919): 0: 936: 100.00		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		1021593 DLG1_HUMAN (1057-1916): 2.05e-154: 501: 19.62		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		990957 ZO1_HUMAN (698-816): 3.52e-09: 64.5: 16.81		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		990904 ZO1_HUMAN (698-816): 3.52e-09: 64.5: 16.81		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		903582 ZO2_HUMAN (1470-1802): 2.6e-11: 71.2: 13.01		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1012561 CGNL1_HUMAN (145-628): 2.87e-10: 67.8: 21.72		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12