Protein: LIN41
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)

Gene: LIN41, TRIM71
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q2Q1W2

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000209 - protein polyubiquitination
GO:0000932 - P-body
GO:0001843 - neural tube closure
GO:0004842 - ubiquitin-protein transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1179707

THAP2
THAP domain-containing protein 2

3

5

High-throughput

0.667

High

1179708

LN28A
Protein lin-28 homolog A

3

13

High-throughput

0.650

High

1179695

LN28B
Protein lin-28 homolog B

2

13

Small-scale

0.646

High

935404

FGF8
Fibroblast growth factor 8

2

1

High-throughput

0.628

High

1179693

E4F1
Transcription factor E4F1

2

20

High-throughput

0.628

High

1179694

Z324B
Zinc finger protein 324B

2

20

High-throughput

0.628

High

244851

TRAK2
Trafficking kinesin-binding protein 2

3

20

High-throughput

0.609

High

1037179

H11
Histone H1.1

3

11

High-throughput

0.609

High

1179713

AGO2
Protein argonaute-2

2

20

Small-scale

0.584

High

50904

SYCE3
Synaptonemal complex central element protein 3

2

1

High-throughput

0.574

High

521716

H14
Histone H1.4

2

11

High-throughput

0.574

High

868354

CDX1
Homeobox protein CDX-1

2

9

High-throughput

0.574

High

1139925

RRS1
Ribosome biogenesis regulatory protein homolog

2

2

High-throughput

0.574

High

1179691

RSBN1
Lysine-specific demethylase 9

2

1

High-throughput

0.574

High

182308

WDR46
WD repeat-containing protein 46

2

17

High-throughput

0.558

High

658208

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.536

High

994571

YBOX1
Y-box-binding protein 1

1

11

High-throughput

0.536

High

1009210

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

1179696

ZN467
Zinc finger protein 467

1

20

High-throughput

0.536

High

1179698

THAP3
THAP domain-containing protein 3

1

5

High-throughput

0.536

High

1179703

ZN668
Zinc finger protein 668

1

20

High-throughput

0.536

High

1179714

ZN346
Zinc finger protein 346

1

3

High-throughput

0.536

High

290581

SURF6
Surfeit locus protein 6

1

6

High-throughput

0.489

High

338849

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.489

High

596130

H12
Histone H1.2

1

12

High-throughput

0.489

High

627346

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

11

High-throughput

0.489

High

842393

RL35
Large ribosomal subunit protein uL29

1

2

High-throughput

0.489

High

969890

RS16
Small ribosomal subunit protein uS9

1

6

High-throughput

0.489

High

984788

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.489

High

1016032

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.489

High

1062004

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.489

High

1112038

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.489

High

1115697

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

18

High-throughput

0.489

High

1179701

FGF13
Fibroblast growth factor 13

1

1

High-throughput

0.489

High

1179702

PABP5
Polyadenylate-binding protein 5

1

15

High-throughput

0.489

High

1179710

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.489

High

1179712

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.489

High

1179716

YBOX2
Y-box-binding protein 2

1

11

High-throughput

0.489

High

400916

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

413940

P53
Cellular tumor antigen p53

1

16

Small-scale

0.479

High

851580

GATA4
Transcription factor GATA-4

1

6

High-throughput

0.479

High

1085566

FOXO1
Forkhead box protein O1

1

7

High-throughput

0.479

High

1155428

EZH2
Histone-lysine N-methyltransferase EZH2

1

19

High-throughput

0.479

High

1179700

RENT1
Regulator of nonsense transcripts 1

1

9

Small-scale

0.479

High

1179709

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

20

Small-scale

0.479

High

1179711

ZRAN1
Ubiquitin thioesterase ZRANB1

1

19

High-throughput

0.479

High

1179715

DICER
Endoribonuclease Dicer

1

20

Small-scale

0.479

High

1179697

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

11

High-throughput

0.445

High

340145

PCNT
Pericentrin

1

20

High-throughput

0.437

High

904789

MECP2
Methyl-CpG-binding protein 2

1

14

High-throughput

0.437

High

960130

RL26
Large ribosomal subunit protein uL24

1

4

High-throughput

0.437

High

1024607

VIGLN
Vigilin

1

20

High-throughput

0.437

High

1062487

DHX9
ATP-dependent RNA helicase A

1

20

Small-scale

0.437

High

1179699

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

3

Small-scale

0.437

High

1179706

SMG1
Serine/threonine-protein kinase SMG1

1

13

Small-scale

0.437

High

72780

B0UZZ8
WD repeat-containing protein 46

1

18

High-throughput

0.407

High

668218

CXCR2
C-X-C chemokine receptor type 2

1

1

Small-scale

0.407

High

1119156

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.407

High

1179690

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.407

High

1179692

CP135
Centrosomal protein of 135 kDa

1

20

High-throughput

0.407

High

1179705

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.407

High

1179704

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025