Protein: 2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)

Gene: 2A5D, PPP2R5D
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q14738

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0004721 - phosphoprotein phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672123

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

11

20

Small-scale

0.982

High

915191

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

8

20

High-throughput

0.975

High

930847

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

7

20

Small-scale

0.972

High

890964

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

4

20

Small-scale

0.909

High

672422

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

4

20

Small-scale

0.900

High

1025287

LIPA1
Liprin-alpha-1

3

4

High-throughput

0.687

High

851771

CCNG1
Cyclin-G1

3

13

High-throughput

0.667

High

1058721

PPME1
Protein phosphatase methylesterase 1

3

1

High-throughput

0.667

High

1058674

SGO1
Shugoshin 1

3

4

Small-scale

0.650

High

871857

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

3

0

High-throughput

0.638

High

1058699

RPGF5
Rap guanine nucleotide exchange factor 5

2

4

High-throughput

0.628

High

1058710

PRR14
Proline-rich protein 14

2

3

High-throughput

0.628

High

905898

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

17

Small-scale

0.618

High

788837

RS27
Small ribosomal subunit protein eS27

2

1

High-throughput

0.611

High

1058671

CCNG2
Cyclin-G2

2

13

High-throughput

0.611

High

881856

WNT3A
Protein Wnt-3a

3

4

High-throughput

0.609

High

1058688

FA43A
Protein FAM43A

3

4

High-throughput

0.609

High

1058697

DNS2B
Deoxyribonuclease-2-beta

3

1

High-throughput

0.609

High

885860

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1058705

BTBD6
BTB/POZ domain-containing protein 6

2

0

High-throughput

0.602

High

1058719

FBXL3
F-box/LRR-repeat protein 3

2

0

High-throughput

0.602

High

1058666

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

8

Small-scale

0.590

High

50912

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

4

High-throughput

0.573

High

1058673

SGO2
Shugoshin 2

2

2

Small-scale

0.562

High

673581

MPIP3
M-phase inducer phosphatase 3

2

0

Small-scale

0.559

High

331288

CHK2
Serine/threonine-protein kinase Chk2

1

6

Small-scale

0.552

High

683351

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.536

High

818052

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.536

High

1021055

FOXF1
Forkhead box protein F1

1

2

High-throughput

0.536

High

1058667

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.536

High

1058686

DNJB7
DnaJ homolog subfamily B member 7

1

1

High-throughput

0.536

High

1058714

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

899121

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

2

Small-scale

0.527

High

1058690

USBP1
Harmonin-binding protein USHBP1

1

1

High-throughput

0.523

High

323758

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

574337

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

602838

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.513

High

1058680

RAD9B
Cell cycle checkpoint control protein RAD9B

1

0

High-throughput

0.513

High

1058692

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1058698

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.513

High

1058700

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1058704

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

1058706

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1058709

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

0

High-throughput

0.513

High

1058712

RDH8
Retinol dehydrogenase 8

1

0

High-throughput

0.513

High

1058722

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.513

High

846413

RORG
Nuclear receptor ROR-gamma

1

1

High-throughput

0.508

High

931636

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.508

High

1058708

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

2

Small-scale

0.501

High

1018894

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

2

High-throughput

0.489

High

1030929

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1058677

TTC27
Tetratricopeptide repeat protein 27

1

3

High-throughput

0.489

High

1058695

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.489

High

181522

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.481

High

236929

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

6

Small-scale

0.481

High

330426

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

2

Small-scale

0.481

High

830360

KC1E
Casein kinase I isoform epsilon

1

2

High-throughput

0.481

High

1058670

CRY1
Cryptochrome-1

1

3

High-throughput

0.481

High

1058672

CRY2
Cryptochrome-2

1

3

High-throughput

0.481

High

227468

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

322639

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

552736

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

651217

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

657494

TMOD1
Tropomodulin-1

1

1

High-throughput

0.479

High

720478

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

940905

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1034856

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1058668

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

1058678

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.479

High

1058679

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1058694

CCHCR
Coiled-coil alpha-helical rod protein 1

1

2

High-throughput

0.479

High

1058701

ARHG2
Rho guanine nucleotide exchange factor 2

1

3

Small-scale

0.479

High

1058713

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

1058716

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

430181

PROF1
Profilin-1

1

0

High-throughput

0.458

High

779419

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

835761

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.458

High

1024013

ACACA
Acetyl-CoA carboxylase 1

1

0

Small-scale

0.458

High

1036578

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1058664

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1058669

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1058685

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1058693

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

1058702

OPTN
Optineurin

1

0

High-throughput

0.458

High

146496

BHE40
Class E basic helix-loop-helix protein 40

1

2

High-throughput

0.457

High

1058687

DZIP1
Cilium assembly protein DZIP1

1

9

Small-scale

0.457

High

1058707

NEK1
Serine/threonine-protein kinase Nek1

1

4

Small-scale

0.457

High

57026

A2ABH1
Coiled-coil alpha-helical rod protein 1

1

1

High-throughput

0.445

High

497027

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

1058689

Q8N5D4
CCNG2 protein

1

13

High-throughput

0.445

High

1058715

DEC1
Deleted in esophageal cancer 1

1

1

High-throughput

0.439

High

1058681

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1058711

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

1058718

DJC12
DnaJ homolog subfamily C member 12

1

1

High-throughput

0.437

High

734464

ARL2
ADP-ribosylation factor-like protein 2

1

0

Small-scale

0.426

High

1029230

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.426

High

176025

GPR37
Prosaposin receptor GPR37

2

0

High-throughput

0.328

High

447618

CEL3A
Chymotrypsin-like elastase family member 3A

2

0

High-throughput

0.328

High

1058691

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.328

High

1058665

PON2
Serum paraoxonase/arylesterase 2

2

0

High-throughput

0.318

High

1058696

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.316

High

354702

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.279

Low

574207

BMP7
Bone morphogenetic protein 7

1

0

High-throughput

0.279

Low

957398

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1058675

VWA2
von Willebrand factor A domain-containing protein 2

1

0

High-throughput

0.279

Low

1058676

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.279

Low

1058682

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.279

Low

1058683

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.279

Low

1058720

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

1058723

CCD61
Centrosomal protein CCDC61

1

0

High-throughput

0.279

Low

123594

PGRC1
Membrane-associated progesterone receptor component 1

1

0

Small-scale

0.249

Low

196304

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

384851

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1058684

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1058703

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1058717

HOOK1
Protein Hook homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024