HitPredict

Interactor 1: Q8WNW7 (Q8WNW7)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha)
Gene: NFKBIA

Interactor 2: NEMO (Q95KU9)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Bos taurus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12459277
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~CC2-LZ
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 314 Bt			1 419
+	Mm
		291826 IKBA_MOUSE (1-314): 2.38e-72: 227: 92.68		NEMO_MOUSE (1-419): 2.74e-51: 179: 83.06
+	Hs
		639834 IKBA_HUMAN (1-314): 8.1e-73: 228: 93.69		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		121608 IKBE_HUMAN (70-312): 3.07e-70: 227: 37.25		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		961453 NFKB2_HUMAN (55-294): 1e-61: 212: 32.93		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		1076400 IKBB_HUMAN (70-311): 2.11e-58: 193: 30.74		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		965180 ANK2_HUMAN (39-312): 1.49e-70: 239: 17.76		MYO5A_HUMAN (26-342): 5.63e-29: 122: 13.73
+	Hs
		883695 RIPK4_HUMAN (81-314): 3.28e-42: 157: 22.13		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		1330909 Q9H4D1_HUMAN (81-314): 7.51e-42: 155: 22.13		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		149043 ANR35_HUMAN (36-301): 1.6e-57: 201: 26.77		CTRO_HUMAN (29-416): 6.77e-29: 121: 13.92
+	Hs
		862142 DAPK1_HUMAN (1-173): 3.75e-36: 139: 15.39		NEMO_HUMAN (1-419): 3.01e-50: 177: 85.68
+	Hs
		787897 ANK2_HUMAN (39-312): 1.49e-70: 239: 17.76		EPS15_HUMAN (7-157): 2.65e-09: 61.5: 9.93
+	Mm
		291802 IKBB_MOUSE (70-287): 1.1e-27: 112: 33.98		NEMO_MOUSE (1-419): 2.74e-51: 179: 83.06
+	Hs
		551669 NFKB2_HUMAN (55-294): 1e-61: 212: 32.93		DESP_HUMAN (22-387): 9.85e-10: 63.1: 15.24
+	Hs
		1216417 TNKS2_HUMAN (45-314): 1.71e-59: 207: 20.82		MY18B_HUMAN (27-358): 8.61e-09: 60: 13.87
+	Hs
		551718 IKBB_HUMAN (70-311): 2.11e-58: 193: 30.74		DESP_HUMAN (22-387): 9.85e-10: 63.1: 15.24
+	Hs
		166927 ANR28_HUMAN (1-170): 7.53e-26: 109: 12.78		DCTN1_HUMAN (63-395): 6.43e-29: 121: 15.94
+	Hs
		1021469 ANK3_HUMAN (151-310): 2.09e-41: 155: 20.63		EP15R_HUMAN (7-172): 6.51e-11: 66.5: 12.05
+	Hs
		1021434 ANK3_HUMAN (151-310): 2.09e-41: 155: 20.63		DLG5_HUMAN (41-387): 3.52e-10: 64.2: 16.67
+	Hs
		1206081 MIB1_HUMAN (81-304): 5.45e-37: 142: 17.18		EP15R_HUMAN (7-172): 6.51e-11: 66.5: 12.05
+	Hs
		787941 MIB1_HUMAN (81-304): 5.45e-37: 142: 17.18		EPS15_HUMAN (7-157): 2.65e-09: 61.5: 9.93