Protein: TP4A3
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)

Gene: TP4A3, PTP4A3
Organism: Homo sapiens
Interactions: 165
UniProt ID: O75365

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0004727 - prenylated protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

260551

TP4A2
Protein tyrosine phosphatase type IVA 2

4

16

High-throughput

0.903

High

260582

CNNM3
Metal transporter CNNM3

2

10

Small-scale

0.776

High

260501

TP4A3
Protein tyrosine phosphatase type IVA 3

1

15

High-throughput

0.618

High

260526

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

High-throughput

0.618

High

117531

MYO1C
Unconventional myosin-Ic

2

12

High-throughput

0.611

High

260527

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

2

8

High-throughput

0.601

High

260574

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

13

High-throughput

0.601

High

260586

IPO4
Importin-4

2

19

High-throughput

0.601

High

260638

FZR1
Fizzy-related protein homolog

1

10

Small-scale

0.561

High

260590

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

13

High-throughput

0.553

High

260537

ITA1
Integrin alpha-1

1

3

Small-scale

0.552

High

260528

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

15

High-throughput

0.541

High

60258

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.536

High

161266

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

15

High-throughput

0.536

High

260504

MYO1D
Unconventional myosin-Id

1

12

High-throughput

0.536

High

260517

SFPQ
Splicing factor, proline- and glutamine-rich

1

3

High-throughput

0.536

High

260524

MYH9
Myosin-9

1

4

High-throughput

0.536

High

260549

EWS
RNA-binding protein EWS

1

3

High-throughput

0.536

High

260550

MYO1E
Unconventional myosin-Ie

1

12

High-throughput

0.536

High

260572

MYH14
Myosin-14

1

4

High-throughput

0.536

High

260579

NIN
Ninein

1

14

High-throughput

0.536

High

260580

PR38A
Pre-mRNA-splicing factor 38A

1

1

High-throughput

0.536

High

260588

CATIN
Splicing factor Cactin

1

3

High-throughput

0.536

High

260595

LRCH3
DISP complex protein LRCH3

1

2

High-throughput

0.536

High

260603

DIDO1
Death-inducer obliterator 1

1

6

High-throughput

0.536

High

260604

ULBP3
UL16-binding protein 3

1

1

High-throughput

0.536

High

260611

MYO5C
Unconventional myosin-Vc

1

4

High-throughput

0.536

High

260618

SLTM
SAFB-like transcription modulator

1

9

High-throughput

0.536

High

260621

ARHGC
Rho guanine nucleotide exchange factor 12

1

3

High-throughput

0.536

High

260628

ZO2
Tight junction protein ZO-2

1

7

High-throughput

0.536

High

260635

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

4

High-throughput

0.536

High

260636

NEB1
Neurabin-1

1

10

High-throughput

0.536

High

260637

MYO5B
Unconventional myosin-Vb

1

2

High-throughput

0.536

High

260640

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

3

High-throughput

0.536

High

260644

MYO5A
Unconventional myosin-Va

1

6

High-throughput

0.536

High

260649

KC1G3
Casein kinase I isoform gamma-3

1

3

High-throughput

0.536

High

260556

CUL2
Cullin-2

2

7

High-throughput

0.533

High

155496

TNPO2
Transportin-2

1

20

High-throughput

0.515

High

198502

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

2

High-throughput

0.515

High

260507

SMC2
Structural maintenance of chromosomes protein 2

1

7

High-throughput

0.515

High

260511

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

High-throughput

0.515

High

260516

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

5

High-throughput

0.515

High

260518

CDK2
Cyclin-dependent kinase 2

1

7

High-throughput

0.515

High

260519

MCM3
DNA replication licensing factor MCM3

1

10

High-throughput

0.515

High

260521

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.515

High

260529

MSH2
DNA mismatch repair protein Msh2

1

5

High-throughput

0.515

High

260558

UBE4A
Ubiquitin conjugation factor E4 A

1

1

High-throughput

0.515

High

260559

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

2

High-throughput

0.515

High

260568

ECM29
Proteasome adapter and scaffold protein ECM29

1

19

High-throughput

0.515

High

260591

GCN1
Stalled ribosome sensor GCN1

1

20

High-throughput

0.515

High

260598

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.515

High

260610

XPO5
Exportin-5

1

14

High-throughput

0.515

High

260616

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.515

High

260633

XPO7
Exportin-7

1

11

High-throughput

0.515

High

260646

SRPRB
Signal recognition particle receptor subunit beta

1

3

High-throughput

0.515

High

260508

SVIL
Supervillin

1

0

High-throughput

0.513

High

260548

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.513

High

260583

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.513

High

260620

NSE4A
Non-structural maintenance of chromosomes element 4 homolog A

1

0

High-throughput

0.513

High

260535

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.493

High

260536

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.493

High

260547

GTF2I
General transcription factor II-I

1

0

High-throughput

0.493

High

260575

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.493

High

260602

CND3
Condensin complex subunit 3

1

0

High-throughput

0.493

High

260607

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.493

High

260567

PR38B
Pre-mRNA-splicing factor 38B

1

3

High-throughput

0.489

High

260571

MPRIP
Myosin phosphatase Rho-interacting protein

1

9

High-throughput

0.489

High

260585

FAT3
Protocadherin Fat 3

1

1

High-throughput

0.489

High

260592

K0232
Uncharacterized protein KIAA0232

1

1

High-throughput

0.489

High

260593

RMXL1
RNA binding motif protein, X-linked-like-1

1

4

High-throughput

0.489

High

260599

SCAFB
Protein SCAF11

1

7

High-throughput

0.489

High

260622

TMOD2
Tropomodulin-2

1

1

High-throughput

0.489

High

260624

RAI14
Ankycorbin

1

14

High-throughput

0.489

High

260544

TPM4
Tropomyosin alpha-4 chain

1

1

High-throughput

0.488

High

160286

AURKA
Aurora kinase A

1

6

Small-scale

0.479

High

173640

SURF4
Surfeit locus protein 4

1

1

High-throughput

0.479

High

214439

MYO1B
Unconventional myosin-Ib

1

12

High-throughput

0.479

High

231028

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

3

High-throughput

0.479

High

240498

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

3

High-throughput

0.479

High

260506

UBR5
E3 ubiquitin-protein ligase UBR5

1

19

High-throughput

0.479

High

260512

OAT
Ornithine aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

260513

4F2
Amino acid transporter heavy chain SLC3A2

1

2

High-throughput

0.479

High

260514

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.479

High

260515

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

260522

DNJA1
DnaJ homolog subfamily A member 1

1

9

High-throughput

0.479

High

260523

MCM7
DNA replication licensing factor MCM7

1

7

High-throughput

0.479

High

260525

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.479

High

260531

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

2

High-throughput

0.479

High

260534

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

10

High-throughput

0.479

High

260539

GEMI4
Gem-associated protein 4

1

3

High-throughput

0.479

High

260540

EPIPL
Epiplakin

1

11

High-throughput

0.479

High

260541

PSME3
Proteasome activator complex subunit 3

1

3

High-throughput

0.479

High

260543

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

260552

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

8

Small-scale

0.479

High

260554

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.479

High

260555

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

10

High-throughput

0.479

High

260557

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

4

High-throughput

0.479

High

260560

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

260576

SMAP1
Stromal membrane-associated protein 1

1

3

High-throughput

0.479

High

260581

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

260584

TBC15
TBC1 domain family member 15

1

2

High-throughput

0.479

High

260600

CHP1
Calcineurin B homologous protein 1

1

2

High-throughput

0.479

High

260601

NP1L4
Nucleosome assembly protein 1-like 4

1

5

High-throughput

0.479

High

260606

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

260608

UN45A
Protein unc-45 homolog A

1

13

High-throughput

0.479

High

260612

TBG2
Tubulin gamma-2 chain

1

7

High-throughput

0.479

High

260614

MDN1
Midasin

1

5

High-throughput

0.479

High

260625

ATX10
Ataxin-10

1

1

High-throughput

0.479

High

260627

DJB11
DnaJ homolog subfamily B member 11

1

8

High-throughput

0.479

High

260630

DDX20
Probable ATP-dependent RNA helicase DDX20

1

2

High-throughput

0.479

High

260631

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.479

High

260641

DICER
Endoribonuclease Dicer

1

12

High-throughput

0.479

High

260642

STRAP
Serine-threonine kinase receptor-associated protein

1

6

High-throughput

0.479

High

260643

DCAF1
DDB1- and CUL4-associated factor 1

1

6

High-throughput

0.479

High

260645

TNPO3
Transportin-3

1

18

High-throughput

0.479

High

260647

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.479

High

240663

USO1
General vesicular transport factor p115

1

11

High-throughput

0.470

High

260520

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.470

High

260566

NU188
Nucleoporin NUP188

1

2

High-throughput

0.470

High

260569

TTC27
Tetratricopeptide repeat protein 27

1

7

High-throughput

0.470

High

260594

KBP
KIF-binding protein

1

1

High-throughput

0.470

High

260609

HEAT1
HEAT repeat-containing protein 1

1

2

High-throughput

0.470

High

260617

ATD3A
ATPase family AAA domain-containing protein 3A

1

8

High-throughput

0.470

High

195870

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.458

High

199244

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.458

High

260505

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

260545

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.458

High

260553

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.458

High

260563

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.458

High

260564

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.458

High

260577

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

260596

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.458

High

260634

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.458

High

260503

LTN1
E3 ubiquitin-protein ligase listerin

1

2

High-throughput

0.437

High

260510

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.437

High

260530

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.437

High

260532

FNTB
Protein farnesyltransferase subunit beta

1

4

High-throughput

0.437

High

260533

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.437

High

260542

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

3

High-throughput

0.437

High

260546

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

1

High-throughput

0.437

High

260561

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

1

High-throughput

0.437

High

260562

UBE3C
Ubiquitin-protein ligase E3C

1

13

High-throughput

0.437

High

260573

HEAT3
HEAT repeat-containing protein 3

1

1

High-throughput

0.437

High

260578

NUP93
Nuclear pore complex protein Nup93

1

3

High-throughput

0.437

High

260587

PDC6I
Programmed cell death 6-interacting protein

1

8

High-throughput

0.437

High

260589

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.437

High

260615

DJC11
DnaJ homolog subfamily C member 11

1

11

High-throughput

0.437

High

260623

HACD3
Very-long-chain

1

3

High-throughput

0.437

High

260629

SEC63
Translocation protein SEC63 homolog

1

14

High-throughput

0.437

High

260632

IPO11
Importin-11

1

12

High-throughput

0.437

High

260648

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

4

High-throughput

0.437

High

260597

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.279

Low

260619

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

260538

TMM33
Transmembrane protein 33

1

0

High-throughput

0.269

Low

49062

A0N4V7
HCG2039797

1

0

High-throughput

0.249

Low

158626

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.249

Low

260502

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.249

Low

260509

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.249

Low

260565

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

260570

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.249

Low

260605

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.249

Low

260613

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low

260626

NCDN
Neurochondrin

1

0

High-throughput

0.249

Low

260639

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024