HitPredict

Interactor 1: NSE1 (Q8WV22)
Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27)
Gene: NSMCE1

Interactor 2: NSE4A (Q9NXX6)
Non-structural maintenance of chromosomes element 4 homolog A (NS4EA) (Non-SMC element 4 homolog A)
Gene: NSMCE4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 18086888, 26186194, 28514442, 30185588, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 266
Hs

1 385
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024