HitPredict

Interactor 1: ZNRF4 (Q8WWF5)
E3 ubiquitin-protein ligase ZNRF4 (EC 2.3.2.27) (Nixin) (RING finger protein 204) (RING-type E3 ubiquitin transferase ZNRF4) (Zinc/RING finger protein 4)
Gene: ZNRF4

Interactor 2: ZDH18 (Q9NUE0)
Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 18) (DHHC-18) (Zinc finger DHHC domain-containing protein 18)
Gene: ZDHHC18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 429 Hs			1 388
+	Hs
		1262547 ZNRF4_HUMAN (1-429): 2.35e-137: 402: 100.00		ZDHC9_HUMAN (64-387): 7.84e-114: 338: 56.58
+	Hs
		1224607 RN149_HUMAN (95-390): 4.12e-66: 218: 18.61		ZDH14_HUMAN (33-369): 7.45e-115: 345: 66.47
+	Hs
		1240845 RN149_HUMAN (95-390): 4.12e-66: 218: 18.61		ZDHC9_HUMAN (64-387): 7.84e-114: 338: 56.58
+	Hs
		1255983 RN128_HUMAN (83-411): 7.87e-62: 207: 17.55		ZDHC5_HUMAN (82-373): 3.17e-76: 251: 34.59
+	Hs
		1148206 RNF43_HUMAN (116-427): 1.04e-45: 170: 17.12		ZDHC5_HUMAN (82-373): 3.17e-76: 251: 34.59
+	Hs
		1148263 RNF43_HUMAN (116-427): 1.04e-45: 170: 17.12		ZDHC8_HUMAN (82-379): 4.1e-75: 249: 36.33