Protein: SIVA
Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP)

Gene: SIVA, SIVA1
Organism: Homo sapiens
Interactions: 46
UniProt ID: O15304

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005175 - CD27 receptor binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

175417

PCNA
Proliferating cell nuclear antigen

3

1

Small-scale

0.665

High

175432

B2CL1
Bcl-2-like protein 1

2

2

Small-scale

0.646

High

175428

XIAP
E3 ubiquitin-protein ligase XIAP

3

0

Small-scale

0.640

High

175420

CD27
CD27 antigen

2

0

Small-scale

0.613

High

175418

STMN1
Stathmin

2

0

Small-scale

0.605

High

175422

AQP1
Aquaporin-1

2

0

High-throughput

0.580

High

175431

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.580

High

175439

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.580

High

175451

ZN446
Zinc finger protein 446

2

0

High-throughput

0.580

High

175447

LPAR2
Lysophosphatidic acid receptor 2

1

1

Small-scale

0.561

High

175414

P53
Cellular tumor antigen p53

2

0

Small-scale

0.559

High

175429

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

Small-scale

0.559

High

175424

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

Small-scale

0.554

High

175421

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

1

Small-scale

0.552

High

175410

MEFV
Pyrin

1

0

Small-scale

0.549

High

175449

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

Small-scale

0.537

High

175444

FOXP3
Forkhead box protein P3

1

0

Small-scale

0.529

High

175448

PXMP2
Peroxisomal membrane protein 2

1

0

Small-scale

0.529

High

175416

BCL2
Apoptosis regulator Bcl-2

1

2

Small-scale

0.527

High

2722

A0A0C4DG38
Inhibitor of growth family member 3

1

1

High-throughput

0.515

High

175413

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.504

High

175425

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.501

High

175442

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.501

High

175411

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.493

High

175452

ING3
Inhibitor of growth protein 3

1

1

High-throughput

0.481

High

175415

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

175427

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

Small-scale

0.480

High

175437

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.480

High

175412

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

Small-scale

0.479

High

175430

BEX3
Protein BEX3

1

0

High-throughput

0.460

High

175445

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.460

High

175433

TRAF2
TNF receptor-associated factor 2

1

0

Small-scale

0.458

High

175434

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

0

Small-scale

0.458

High

175446

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

175450

FAIM1
Fas apoptotic inhibitory molecule 1

1

0

Small-scale

0.458

High

175453

TNR18
Tumor necrosis factor receptor superfamily member 18

1

1

Small-scale

0.437

High

175426

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.316

High

175435

CB068
UPF0561 protein C2orf68

2

0

High-throughput

0.316

High

175436

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.316

High

175438

AP2D
Transcription factor AP-2-delta

2

0

High-throughput

0.316

High

175440

CTSR1
Cation channel sperm-associated protein 1

2

0

High-throughput

0.316

High

175441

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

175423

ABL2
Tyrosine-protein kinase ABL2

1

0

Small-scale

0.292

High

175443

SSBP3
Single-stranded DNA-binding protein 3

1

0

Small-scale

0.292

High

174252

TELT
Telethonin

1

0

Small-scale

0.275

Low

175419

TA2R
Thromboxane A2 receptor

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024