Protein: ARRD3
Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP)

Gene: ARRD3, ARRDC3
Organism: Homo sapiens
Interactions: 235
UniProt ID: Q96B67

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

458460

ADRB2
Beta-2 adrenergic receptor

6

10

Small-scale

0.948

High

296546

STAM2
Signal transducing adapter molecule 2

3

10

High-throughput

0.871

High

669396

PAR1
Proteinase-activated receptor 1

2

16

Small-scale

0.768

High

732664

ARRB2
Beta-arrestin-2

2

16

Small-scale

0.754

High

1384109

NED4L
E3 ubiquitin-protein ligase NEDD4-like

8

20

Small-scale

0.754

High

861715

NEDD4
E3 ubiquitin-protein ligase NEDD4

8

20

Small-scale

0.753

High

1384128

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

8

20

Small-scale

0.750

High

132217

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

7

20

Small-scale

0.750

High

1384104

ITCH
E3 ubiquitin-protein ligase Itchy homolog

6

20

Small-scale

0.739

High

882542

ARRB1
Beta-arrestin-1

2

16

Small-scale

0.737

High

1091705

MYO1E
Unconventional myosin-Ie

1

16

High-throughput

0.691

High

1384141

WWOX
WW domain-containing oxidoreductase

5

0

High-throughput

0.685

High

255542

HPGDS
Hematopoietic prostaglandin D synthase

3

1

High-throughput

0.675

High

639283

TNAP3
Tumor necrosis factor alpha-induced protein 3

3

3

High-throughput

0.675

High

1384099

DCNL1
DCN1-like protein 1

3

1

High-throughput

0.675

High

1384143

HECW2
E3 ubiquitin-protein ligase HECW2

3

20

High-throughput

0.662

High

347859

BAG3
BAG family molecular chaperone regulator 3

3

0

High-throughput

0.646

High

163342

TR10B
Tumor necrosis factor receptor superfamily member 10B

2

3

High-throughput

0.628

High

650338

FGFR3
Fibroblast growth factor receptor 3

2

4

High-throughput

0.628

High

787225

BMR1A
Bone morphogenetic protein receptor type-1A

2

4

High-throughput

0.628

High

1102738

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

4

High-throughput

0.628

High

1384134

CD320
CD320 antigen

2

3

High-throughput

0.628

High

1384167

KC1G3
Casein kinase I isoform gamma-3

2

11

High-throughput

0.628

High

1384127

TOLIP
Toll-interacting protein

3

0

High-throughput

0.620

High

1312034

DJC10
DnaJ homolog subfamily C member 10

1

6

High-throughput

0.618

High

569043

ADRB3
Beta-3 adrenergic receptor

1

10

Small-scale

0.618

High

1384106

UB2E2
Ubiquitin-conjugating enzyme E2 E2

3

7

High-throughput

0.616

High

861244

MAP1B
Microtubule-associated protein 1B

2

17

Small-scale

0.611

High

329476

EPN2
Epsin-2

2

5

High-throughput

0.606

High

906734

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

7

High-throughput

0.606

High

930771

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

4

High-throughput

0.606

High

943807

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

1

High-throughput

0.606

High

987443

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

15

High-throughput

0.606

High

992903

RACK1
Small ribosomal subunit protein RACK1

2

6

High-throughput

0.606

High

1384096

OPTN
Optineurin

2

7

High-throughput

0.606

High

1384117

UBAC1
Ubiquitin-associated domain-containing protein 1

2

1

High-throughput

0.606

High

1384135

RAD18
E3 ubiquitin-protein ligase RAD18

2

2

High-throughput

0.606

High

1384147

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.606

High

1384148

UBQL2
Ubiquilin-2

2

20

High-throughput

0.606

High

1384138

CUED1
CUE domain-containing protein 1

3

1

High-throughput

0.604

High

1334499

RN149
E3 ubiquitin-protein ligase RNF149

2

0

High-throughput

0.602

High

862357

YAP1
Transcriptional coactivator YAP1

2

20

Small-scale

0.584

High

1308873

CCD50
Coiled-coil domain-containing protein 50

2

0

High-throughput

0.580

High

1384150

RABX5
Rab5 GDP/GTP exchange factor

2

0

High-throughput

0.580

High

1257283

STXB4
Syntaxin-binding protein 4

2

6

High-throughput

0.574

High

210326

PHF1
PHD finger protein 1

2

1

High-throughput

0.553

High

351579

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

1

High-throughput

0.553

High

982274

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

7

High-throughput

0.553

High

1381177

UB2E3
Ubiquitin-conjugating enzyme E2 E3

2

7

High-throughput

0.553

High

1368285

STAM1
Signal transducing adapter molecule 1

1

8

Small-scale

0.553

High

48733

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.536

High

140391

SDCB1
Syntenin-1

1

4

High-throughput

0.536

High

212300

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.536

High

254202

CTND1
Catenin delta-1

1

2

High-throughput

0.536

High

279065

TRIM3
Tripartite motif-containing protein 3

1

3

High-throughput

0.536

High

289647

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

7

High-throughput

0.536

High

317583

SLIT2
Slit homolog 2 protein

1

1

High-throughput

0.536

High

320583

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

7

High-throughput

0.536

High

334073

SMC2
Structural maintenance of chromosomes protein 2

1

4

High-throughput

0.536

High

348182

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

8

High-throughput

0.536

High

522719

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.536

High

540066

BCR
Breakpoint cluster region protein

1

5

High-throughput

0.536

High

547473

DMD
Dystrophin

1

13

High-throughput

0.536

High

637937

NF1
Neurofibromin

1

3

High-throughput

0.536

High

807521

IF4A3
Eukaryotic initiation factor 4A-III

1

7

High-throughput

0.536

High

856852

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.536

High

862687

UTRN
Utrophin

1

11

High-throughput

0.536

High

921983

COPA
Coatomer subunit alpha

1

2

High-throughput

0.536

High

933461

S12A2
Solute carrier family 12 member 2

1

2

High-throughput

0.536

High

997923

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.536

High

1025495

CDK5
Cyclin-dependent kinase 5

1

3

High-throughput

0.536

High

1061081

SRSF1
Serine/arginine-rich splicing factor 1

1

4

High-throughput

0.536

High

1066741

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.536

High

1089248

TRI26
Tripartite motif-containing protein 26

1

2

High-throughput

0.536

High

1090169

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

7

High-throughput

0.536

High

1095159

RED
Protein Red

1

5

High-throughput

0.536

High

1104857

SNTB2
Beta-2-syntrophin

1

3

High-throughput

0.536

High

1107447

BIRC2
Baculoviral IAP repeat-containing protein 2

1

6

High-throughput

0.536

High

1110388

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

2

High-throughput

0.536

High

1110527

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

2

High-throughput

0.536

High

1111473

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

3

High-throughput

0.536

High

1115885

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

1120793

DSG2
Desmoglein-2

1

2

High-throughput

0.536

High

1122304

SCRIB
Protein scribble homolog

1

4

High-throughput

0.536

High

1125180

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

3

High-throughput

0.536

High

1134023

ZN638
Zinc finger protein 638

1

4

High-throughput

0.536

High

1134507

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

10

High-throughput

0.536

High

1134678

NUMA1
Nuclear mitotic apparatus protein 1

1

7

High-throughput

0.536

High

1135035

CUL7
Cullin-7

1

5

High-throughput

0.536

High

1145314

RNPS1
RNA-binding protein with serine-rich domain 1

1

10

High-throughput

0.536

High

1146328

L2GL1
Lethal(2) giant larvae protein homolog 1

1

4

High-throughput

0.536

High

1160028

SRSF7
Serine/arginine-rich splicing factor 7

1

6

High-throughput

0.536

High

1180242

SMU1
WD40 repeat-containing protein SMU1

1

6

High-throughput

0.536

High

1197047

AMOT
Angiomotin

1

4

High-throughput

0.536

High

1244366

SKI3
Superkiller complex protein 3

1

4

High-throughput

0.536

High

1245401

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

High-throughput

0.536

High

1245692

LARP1
La-related protein 1

1

6

High-throughput

0.536

High

1271484

DHX30
ATP-dependent RNA helicase DHX30

1

10

High-throughput

0.536

High

1295439

C2CD5
C2 domain-containing protein 5

1

1

High-throughput

0.536

High

1308689

FMNL3
Formin-like protein 3

1

2

High-throughput

0.536

High

1311259

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

3

High-throughput

0.536

High

1353241

PARD3
Partitioning defective 3 homolog

1

6

High-throughput

0.536

High

1365722

GCN1
Stalled ribosome sensor GCN1

1

15

High-throughput

0.536

High

1371048

ARHG2
Rho guanine nucleotide exchange factor 2

1

5

High-throughput

0.536

High

1384098

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

2

High-throughput

0.536

High

1384105

VPS39
Vam6/Vps39-like protein

1

3

High-throughput

0.536

High

1384107

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.536

High

1384108

IPO9
Importin-9

1

12

High-throughput

0.536

High

1384114

SMAD5
Mothers against decapentaplegic homolog 5

1

1

High-throughput

0.536

High

1384115

DDX50
ATP-dependent RNA helicase DDX50

1

2

High-throughput

0.536

High

1384119

RFIP5
Rab11 family-interacting protein 5

1

10

High-throughput

0.536

High

1384120

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.536

High

1384121

TRIM5
Tripartite motif-containing protein 5

1

2

High-throughput

0.536

High

1384122

TRIM4
E3 ubiquitin-protein ligase TRIM4

1

2

High-throughput

0.536

High

1384123

ZCHC2
Zinc finger CCHC domain-containing protein 2

1

2

High-throughput

0.536

High

1384129

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

2

High-throughput

0.536

High

1384130

PININ
Pinin

1

10

High-throughput

0.536

High

1384131

E41LB
Band 4.1-like protein 4B

1

8

High-throughput

0.536

High

1384133

WDR6
tRNA

1

5

High-throughput

0.536

High

1384139

MIOS
GATOR2 complex protein MIOS

1

1

High-throughput

0.536

High

1384140

BCLF1
Bcl-2-associated transcription factor 1

1

8

High-throughput

0.536

High

1384151

TNIK
TRAF2 and NCK-interacting protein kinase

1

5

High-throughput

0.536

High

1384156

RUVB2
RuvB-like 2

1

4

High-throughput

0.536

High

1384158

SAC2
Phosphatidylinositide phosphatase SAC2

1

1

High-throughput

0.536

High

1384159

E41L3
Band 4.1-like protein 3

1

8

High-throughput

0.536

High

1384164

DTNA
Dystrobrevin alpha

1

8

High-throughput

0.536

High

1311453

TRI42
Tripartite motif-containing protein 42

1

11

High-throughput

0.523

High

169690

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

8

Small-scale

0.515

High

592684

ITB4
Integrin beta-4

1

5

Small-scale

0.515

High

138395

ZN593
Zinc finger protein 593

1

0

High-throughput

0.513

High

158282

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

336229

ZIC2
Zinc finger protein ZIC 2

1

0

High-throughput

0.513

High

1131021

LPIN1
Phosphatidate phosphatase LPIN1

1

0

High-throughput

0.513

High

1384144

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.513

High

1288687

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

20

Small-scale

0.508

High

175749

SR140
U2 snRNP-associated SURP motif-containing protein

1

4

High-throughput

0.489

High

216771

HTRA2
Serine protease HTRA2, mitochondrial

1

2

High-throughput

0.489

High

228099

PM34
Peroxisomal membrane protein PMP34

1

2

High-throughput

0.489

High

251640

CCNT1
Cyclin-T1

1

4

High-throughput

0.489

High

280760

PR40A
Pre-mRNA-processing factor 40 homolog A

1

20

High-throughput

0.489

High

337792

SGPL1
Sphingosine-1-phosphate lyase 1

1

1

High-throughput

0.489

High

625547

CSK22
Casein kinase II subunit alpha'

1

8

High-throughput

0.489

High

667398

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.489

High

669967

MCM3
DNA replication licensing factor MCM3

1

7

High-throughput

0.489

High

685677

U2AF2
Splicing factor U2AF 65 kDa subunit

1

5

High-throughput

0.489

High

756004

MCM5
DNA replication licensing factor MCM5

1

4

High-throughput

0.489

High

756297

MCM7
DNA replication licensing factor MCM7

1

4

High-throughput

0.489

High

773593

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.489

High

897934

CDK9
Cyclin-dependent kinase 9

1

13

High-throughput

0.489

High

935587

MFAP1
Microfibrillar-associated protein 1

1

4

High-throughput

0.489

High

1083418

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.489

High

1088720

SF3A3
Splicing factor 3A subunit 3

1

2

High-throughput

0.489

High

1091865

ABR
Active breakpoint cluster region-related protein

1

6

High-throughput

0.489

High

1147550

UBE3C
Ubiquitin-protein ligase E3C

1

20

High-throughput

0.489

High

1206952

CEP78
Centrosomal protein of 78 kDa

1

5

High-throughput

0.489

High

1225963

F91A1
Protein FAM91A1

1

1

High-throughput

0.489

High

1249393

CWC27
Spliceosome-associated protein CWC27 homolog

1

2

High-throughput

0.489

High

1250026

WDR82
WD repeat-containing protein 82

1

7

High-throughput

0.489

High

1279880

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

12

High-throughput

0.489

High

1290636

ZCH18
Zinc finger CCCH domain-containing protein 18

1

10

High-throughput

0.489

High

1309698

WDR75
WD repeat-containing protein 75

1

4

High-throughput

0.489

High

1336746

RB15B
Putative RNA-binding protein 15B

1

6

High-throughput

0.489

High

1341119

WDR36
WD repeat-containing protein 36

1

3

High-throughput

0.489

High

1357402

DEP1B
DEP domain-containing protein 1B

1

4

High-throughput

0.489

High

1383431

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.489

High

1384101

PDLI5
PDZ and LIM domain protein 5

1

1

High-throughput

0.489

High

1384102

SPF45
Splicing factor 45

1

2

High-throughput

0.489

High

1384110

FMNL2
Formin-like protein 2

1

2

High-throughput

0.489

High

1384112

RBM15
RNA-binding protein 15

1

5

High-throughput

0.489

High

1384113

MINT
Msx2-interacting protein

1

7

High-throughput

0.489

High

1384116

GPTC1
G patch domain-containing protein 1

1

6

High-throughput

0.489

High

1384118

GTPB2
GTP-binding protein 2

1

7

High-throughput

0.489

High

1384125

WDR33
pre-mRNA 3' end processing protein WDR33

1

6

High-throughput

0.489

High

1384132

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

5

High-throughput

0.489

High

1384136

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

1384137

DDX28
Probable ATP-dependent RNA helicase DDX28

1

4

High-throughput

0.489

High

1384142

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

2

High-throughput

0.489

High

1384145

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.489

High

1384149

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

3

High-throughput

0.489

High

1384152

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

2

High-throughput

0.489

High

1384153

GPTC8
G patch domain-containing protein 8

1

13

High-throughput

0.489

High

1384155

MAGD2
Melanoma-associated antigen D2

1

4

High-throughput

0.489

High

1384157

RUVB1
RuvB-like 1

1

4

High-throughput

0.489

High

1384160

DDX52
Probable ATP-dependent RNA helicase DDX52

1

3

High-throughput

0.489

High

1384162

TR150
Thyroid hormone receptor-associated protein 3

1

16

High-throughput

0.489

High

1356972

PDC6I
Programmed cell death 6-interacting protein

1

7

Small-scale

0.481

High

622657

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

3

Small-scale

0.479

High

691317

1433T
14-3-3 protein theta

1

11

Small-scale

0.479

High

710418

EPHA2
Ephrin type-A receptor 2

1

8

Small-scale

0.479

High

720299

UFO
Tyrosine-protein kinase receptor UFO

1

7

Small-scale

0.479

High

925578

MOT1
Monocarboxylate transporter 1

1

4

Small-scale

0.479

High

953961

IF4A1
Eukaryotic initiation factor 4A-I

1

6

High-throughput

0.479

High

1134320

IMB1
Importin subunit beta-1

1

20

Small-scale

0.479

High

1246140

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

3

Small-scale

0.479

High

1371493

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

Small-scale

0.479

High

1384124

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

9

Small-scale

0.479

High

1384126

WWTR1
WW domain-containing transcription regulator protein 1

1

20

Small-scale

0.479

High

256493

TOM1
Target of Myb1 membrane trafficking protein

1

9

High-throughput

0.445

High

484198

PGFRB
Platelet-derived growth factor receptor beta

1

6

High-throughput

0.445

High

839492

PI4KA
Phosphatidylinositol 4-kinase alpha

1

14

High-throughput

0.445

High

1256350

AN13D
Ankyrin repeat domain-containing protein 13D

1

6

High-throughput

0.445

High

1256897

TM1L2
TOM1-like protein 2

1

9

High-throughput

0.445

High

1260706

HECW1
E3 ubiquitin-protein ligase HECW1

1

20

High-throughput

0.445

High

1315826

AN13A
Ankyrin repeat domain-containing protein 13A

1

4

High-throughput

0.445

High

1322616

RPTOR
Regulatory-associated protein of mTOR

1

5

High-throughput

0.445

High

1384154

MYO6
Unconventional myosin-VI

1

10

High-throughput

0.445

High

1195678

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

13

High-throughput

0.437

High

1384097

OTUB2
Ubiquitin thioesterase OTUB2

3

0

High-throughput

0.352

High

733850

CDD
Cytidine deaminase

2

0

High-throughput

0.316

High

832764

BCL6
B-cell lymphoma 6 protein

2

0

High-throughput

0.316

High

1295080

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1384100

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1384146

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.299

High

71750

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.279

Low

134821

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.279

Low

301938

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.279

Low

703020

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.279

Low

895627

SERPH
Serpin H1

1

0

High-throughput

0.279

Low

1092710

AF1Q
Protein AF1q

1

0

High-throughput

0.279

Low

1111174

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1226414

TBC9B
TBC1 domain family member 9B

1

0

High-throughput

0.279

Low

1240250

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.279

Low

1243216

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

1248055

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.279

Low

1258665

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low

1384161

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.279

Low

1384163

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.279

Low

1384165

PAXB1
PAX3- and PAX7-binding protein 1

1

0

High-throughput

0.279

Low

1384166

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.279

Low

1384168

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.279

Low

1291821

T200A
Transmembrane protein 200A

1

0

Small-scale

0.249

Low

1308183

PLD3
5'-3' exonuclease PLD3

1

0

Small-scale

0.249

Low

1384103

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

Small-scale

0.249

Low

1151971

TWST1
Twist-related protein 1

1

0

Small-scale

0.238

Low

1384111

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025