HitPredict

Interactor 1: ING5 (Q8WYH8)
Inhibitor of growth protein 5 (p28ING5)
Gene: ING5

Interactor 2: EAF6 (Q9HAF1)
Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91)
Gene: MEAF6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 24981860, 16387653, 18794358
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ING~NuA4
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0001558 - regulation of cell growth GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006275 - regulation of DNA replication and 6 others more... GO:0006355 - regulation of DNA-templated transcription GO:0050793 - regulation of developmental process GO:0051726 - regulation of cell cycle GO:0070776 - MOZ/MORF histone acetyltransferase complex GO:1903706 - regulation of hemopoiesis GO:2000278 - regulation of DNA biosynthetic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	240
Hs

1	191

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024