Protein: MAK16
Protein MAK16 homolog (NNP78) (Protein RBM13)

Gene: MAK16
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9BXY0

Gene Ontology (top 5):
GO:0000460 - maturation of 5.8S rRNA
GO:0000470 - maturation of LSU-rRNA
GO:0003723 - RNA binding
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

985547

RL32
Large ribosomal subunit protein eL32

4

0

High-throughput

0.849

High

940173

RRP1
Ribosomal RNA processing protein 1 homolog A

2

3

High-throughput

0.811

High

1351464

BRX1
Ribosome biogenesis protein BRX1 homolog

2

12

High-throughput

0.811

High

1417562

RPF2
Ribosome production factor 2 homolog

2

2

High-throughput

0.811

High

1417563

RPF1
Ribosome production factor 1

2

5

High-throughput

0.811

High

785416

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.770

High

1417566

SSF1
Suppressor of SWI4 1 homolog

1

3

High-throughput

0.691

High

447394

NPM
Nucleophosmin

3

1

High-throughput

0.667

High

615956

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.656

High

338183

NSA2
Ribosome biogenesis protein NSA2 homolog

2

1

High-throughput

0.628

High

517698

ZBT48
Zinc finger and BTB domain-containing protein 48

2

1

High-throughput

0.628

High

521912

H14
Histone H1.4

2

2

High-throughput

0.628

High

841452

RBM34
RNA-binding protein 34

2

1

High-throughput

0.628

High

977070

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

1

High-throughput

0.628

High

987193

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

1

High-throughput

0.628

High

1043748

CEBPZ
CCAAT/enhancer-binding protein zeta

2

1

High-throughput

0.628

High

1112157

KRR1
KRR1 small subunit processome component homolog

2

1

High-throughput

0.628

High

1148159

PUM3
Pumilio homolog 3

2

1

High-throughput

0.628

High

1247288

WDR74
WD repeat-containing protein 74

2

4

High-throughput

0.628

High

1314228

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

2

High-throughput

0.628

High

1327380

ZCHC9
Zinc finger CCHC domain-containing protein 9

2

2

High-throughput

0.628

High

1356028

NOC3L
Nucleolar complex protein 3 homolog

2

5

High-throughput

0.628

High

1392228

DDX27
Probable ATP-dependent RNA helicase DDX27

2

3

High-throughput

0.628

High

1407694

EBP2
Probable rRNA-processing protein EBP2

2

2

High-throughput

0.628

High

1417561

DDX24
ATP-dependent RNA helicase DDX24

2

4

High-throughput

0.628

High

1417572

RBM28
RNA-binding protein 28

2

1

High-throughput

0.628

High

1417584

RLP24
Probable ribosome biogenesis protein RLP24

2

2

High-throughput

0.628

High

1417592

NOC2L
Nucleolar complex protein 2 homolog

2

1

High-throughput

0.628

High

984955

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.611

High

1161645

IF16
Gamma-interferon-inducible protein 16

2

1

High-throughput

0.611

High

1417589

RL26L
Ribosomal protein uL24-like

2

1

High-throughput

0.611

High

188526

NVL
Nuclear valosin-containing protein-like

2

0

High-throughput

0.602

High

208366

RRP8
Ribosomal RNA-processing protein 8

2

0

High-throughput

0.602

High

290714

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.602

High

859434

RL5
Large ribosomal subunit protein uL18

2

0

High-throughput

0.602

High

975915

RL7A
Large ribosomal subunit protein eL8

2

0

High-throughput

0.602

High

982539

RS15
Small ribosomal subunit protein uS19

2

0

High-throughput

0.602

High

984527

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

1028376

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

High-throughput

0.602

High

1168566

KNOP1
Lysine-rich nucleolar protein 1

2

0

High-throughput

0.602

High

1275650

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

0

High-throughput

0.602

High

1348842

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

2

0

High-throughput

0.602

High

1361752

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

810338

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.585

High

96758

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

979200

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.584

High

1130430

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.575

High

1417578

H2AW
Core histone macro-H2A.2

2

2

High-throughput

0.574

High

287119

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

2

High-throughput

0.536

High

288755

NPM3
Nucleoplasmin-3

1

1

High-throughput

0.536

High

301193

RL1D1
Ribosomal L1 domain-containing protein 1

1

2

High-throughput

0.536

High

428955

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

476802

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.536

High

596330

H12
Histone H1.2

1

2

High-throughput

0.536

High

833178

MNDA
Myeloid cell nuclear differentiation antigen

1

1

High-throughput

0.536

High

855204

NOP2
28S rRNA

1

2

High-throughput

0.536

High

959944

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.536

High

1006678

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.536

High

1061127

SRSF1
Serine/arginine-rich splicing factor 1

1

3

High-throughput

0.536

High

1062102

SRSF4
Serine/arginine-rich splicing factor 4

1

5

High-throughput

0.536

High

1099228

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.536

High

1099515

SRSF6
Serine/arginine-rich splicing factor 6

1

5

High-throughput

0.536

High

1130835

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.536

High

1417558

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.536

High

1417559

GTPB4
GTP-binding protein 4

1

3

High-throughput

0.536

High

1417564

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

302945

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

2

High-throughput

0.533

High

257958

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.513

High

686395

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

788763

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

824333

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

842515

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

854273

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

859979

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

898800

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

938795

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

0

High-throughput

0.513

High

985862

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

986182

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1016198

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1395810

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1405609

TSNAX
Translin-associated protein X

1

0

High-throughput

0.513

High

1409828

RBM4B
RNA-binding protein 4B

1

0

High-throughput

0.513

High

1410717

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

1411886

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

1417570

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

1417573

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

1417574

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.513

High

1417576

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.513

High

1417583

NOL12
Nucleolar protein 12

1

0

High-throughput

0.513

High

1417586

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1417587

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

997994

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.502

High

502518

H2A1
Histone H2A type 1

1

1

High-throughput

0.489

High

625599

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.489

High

1037350

H11
Histone H1.1

1

2

High-throughput

0.489

High

1307317

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.489

High

1313135

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

1

High-throughput

0.489

High

1385560

ZN524
Zinc finger protein 524

1

1

High-throughput

0.489

High

1417582

ZBT47
Zinc finger and BTB domain-containing protein 47

1

1

High-throughput

0.489

High

1417590

SRPK3
SRSF protein kinase 3

1

1

High-throughput

0.489

High

346280

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

373059

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406597

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

612767

RL7
Large ribosomal subunit protein uL30

1

2

High-throughput

0.479

High

1387542

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

644029

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

982803

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

1127136

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

1417560

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1417571

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1417580

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1212367

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

401428

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

965214

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1338940

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.437

High

69974

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

1398976

FRMD6
FERM domain-containing protein 6

4

0

High-throughput

0.364

High

1412385

ZNF2
Zinc finger protein 2

2

0

High-throughput

0.328

High

1417575

TBA8
Tubulin alpha-8 chain

2

0

High-throughput

0.328

High

1417565

LIN7B
Protein lin-7 homolog B

2

0

High-throughput

0.316

High

1417568

ANLN
Anillin

2

0

High-throughput

0.305

High

396867

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

137479

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.279

Low

191789

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

440713

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.279

Low

593486

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.279

Low

897162

TUB
Tubby protein homolog

1

0

High-throughput

0.279

Low

996526

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.279

Low

1127483

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1210526

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.279

Low

1331762

JMY
Junction-mediating and -regulatory protein

1

0

High-throughput

0.279

Low

1390594

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.279

Low

1395698

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1398575

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.279

Low

1399812

TECTB
Beta-tectorin

1

0

High-throughput

0.279

Low

1402667

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.279

Low

1417567

PAK6
Serine/threonine-protein kinase PAK 6

1

0

High-throughput

0.279

Low

1417569

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

1

0

High-throughput

0.279

Low

1417577

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

1417579

NHSL3
NHS-like protein 3

1

0

High-throughput

0.279

Low

1417581

POLK
DNA polymerase kappa

1

0

High-throughput

0.279

Low

1417585

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

157810

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

242813

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

248074

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

879434

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1107172

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

1255388

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1380738

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.249

Low

1385614

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.249

Low

1403566

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.249

Low

1417588

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1417591

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025