Interactor 1: SIG12 (Q91Y57)
Sialic acid-binding Ig-like lectin 12 (Siglec-12) (Myeloid inhibitory siglec) (MIS) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (Sialic acid-binding Ig-like lectin E) (Siglec-E) (mSiglec-E) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1)
Gene: Siglec12

Interactor 2: SIG12 (Q91Y57)
Sialic acid-binding Ig-like lectin 12 (Siglec-12) (Myeloid inhibitory siglec) (MIS) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (Sialic acid-binding Ig-like lectin E) (Siglec-E) (mSiglec-E) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1)
Gene: Siglec12

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 11171044
Identification Methods affinity chromatography technology, comigration in non denaturing gel electrophoresis
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0006911 - phagocytosis, engulfment
GO:0006954 - inflammatory response
GO:0009897 - external side of plasma membrane
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 467
Mm

1 467
+ Mm
+ Mm
+ Hs
+ Dr
+ Dm
+ Hs
+ Dr
+ Hs
+ Hs
+ Dm
+ Dm
+ Dr
+ Dr
+ Ce
+ Hs
+ Dr
+ Hs
+ Hs

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Last updated: 15 Jul 2024