Protein: PUM1
Pumilio homolog 1 (HsPUM) (Pumilio-1)

Gene: PUM1
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q14671

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

683348

1433B
14-3-3 protein beta/alpha

3

6

High-throughput

0.678

High

198888

RFOX2
RNA binding protein fox-1 homolog 2

3

10

High-throughput

0.667

High

1020260

ELAV2
ELAV-like protein 2

2

10

High-throughput

0.628

High

1056693

CLASR
CLK4-associating serine/arginine rich protein

2

1

High-throughput

0.628

High

1056694

CELF5
CUGBP Elav-like family member 5

2

9

High-throughput

0.628

High

1056730

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

1

High-throughput

0.628

High

1056703

PUM2
Pumilio homolog 2

1

6

High-throughput

0.618

High

47775

RBM47
RNA-binding protein 47

2

9

High-throughput

0.611

High

181195

NUP42
Nucleoporin NUP42

2

1

High-throughput

0.611

High

1056653

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

2

12

High-throughput

0.611

High

1056710

LAR4B
La-related protein 4B

2

5

High-throughput

0.611

High

1056764

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

3

High-throughput

0.611

High

1056721

TRI11
E3 ubiquitin-protein ligase TRIM11

2

0

High-throughput

0.602

High

1056768

CNOT8
CCR4-NOT transcription complex subunit 8

2

9

Small-scale

0.595

High

1030239

G3BP1
Ras GTPase-activating protein-binding protein 1

2

8

High-throughput

0.584

High

1056667

RC3H1
Roquin-1

2

1

High-throughput

0.584

High

1056687

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

2

High-throughput

0.584

High

321079

PTBP3
Polypyrimidine tract-binding protein 3

2

5

High-throughput

0.571

High

909565

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.565

High

646889

1433T
14-3-3 protein theta

1

6

High-throughput

0.554

High

904562

1433G
14-3-3 protein gamma

1

6

High-throughput

0.554

High

927044

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.554

High

982012

1433F
14-3-3 protein eta

1

6

High-throughput

0.554

High

181521

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.536

High

201671

MSI1H
RNA-binding protein Musashi homolog 1

1

9

High-throughput

0.536

High

432711

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

7

High-throughput

0.536

High

793959

MATR3
Matrin-3

1

2

High-throughput

0.536

High

877610

FOXG1
Forkhead box protein G1

1

1

High-throughput

0.536

High

1019496

ILF2
Interleukin enhancer-binding factor 2

1

4

High-throughput

0.536

High

1056657

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

2

High-throughput

0.536

High

1056684

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1056690

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

6

High-throughput

0.536

High

1056717

SPSB4
SPRY domain-containing SOCS box protein 4

1

7

High-throughput

0.536

High

1056720

PABP5
Polyadenylate-binding protein 5

1

6

High-throughput

0.536

High

1056728

SPSB2
SPRY domain-containing SOCS box protein 2

1

7

High-throughput

0.536

High

1056737

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

8

High-throughput

0.536

High

1056750

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.536

High

1056772

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.536

High

1056725

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

0

High-throughput

0.528

High

873843

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.518

High

684037

1433S
14-3-3 protein sigma

1

6

High-throughput

0.515

High

176024

GPR37
Prosaposin receptor GPR37

1

1

High-throughput

0.515

High

164893

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.513

High

323754

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

504084

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

621782

PRTN3
Myeloblastin

1

0

High-throughput

0.513

High

813473

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

945253

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1056715

CSN5
COP9 signalosome complex subunit 5

1

5

Small-scale

0.501

High

1056777

PRR12
Proline-rich protein 12

1

1

High-throughput

0.494

High

660493

GRN
Progranulin

1

0

High-throughput

0.493

High

1056676

FOXI2
Forkhead box protein I2

1

1

High-throughput

0.489

High

1056724

LOXL4
Lysyl oxidase homolog 4

1

1

High-throughput

0.489

High

1056738

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.489

High

868491

ATX1
Ataxin-1

1

0

High-throughput

0.486

High

1056654

SMAD1
Mothers against decapentaplegic homolog 1

1

0

High-throughput

0.486

High

50016

MEX3A
RNA-binding protein MEX3A

1

11

High-throughput

0.479

High

61366

CNOT1
CCR4-NOT transcription complex subunit 1

1

4

High-throughput

0.479

High

87471

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

1

High-throughput

0.479

High

118557

EYA2
Eyes absent homolog 2

1

1

High-throughput

0.479

High

118865

GTPB1
GTP-binding protein 1

1

6

High-throughput

0.479

High

122755

MEN1
Menin

1

1

High-throughput

0.479

High

128178

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

9

High-throughput

0.479

High

134042

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

High-throughput

0.479

High

162743

XPO1
Exportin-1

1

8

High-throughput

0.479

High

170366

TIF1A
Transcription intermediary factor 1-alpha

1

3

Small-scale

0.479

High

227459

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

235863

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

8

High-throughput

0.479

High

257355

CNOT3
CCR4-NOT transcription complex subunit 3

1

8

High-throughput

0.479

High

257614

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.479

High

311343

CELF2
CUGBP Elav-like family member 2

1

10

High-throughput

0.479

High

322629

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

346788

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

384842

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

442161

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

High-throughput

0.479

High

516519

PABP1
Polyadenylate-binding protein 1

1

6

High-throughput

0.479

High

603502

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

615734

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

640478

DDX6
Probable ATP-dependent RNA helicase DDX6

1

9

High-throughput

0.479

High

644252

TTP
mRNA decay activator protein ZFP36

1

4

High-throughput

0.479

High

668357

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

14

High-throughput

0.479

High

717823

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

779412

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

815247

TISD
mRNA decay activator protein ZFP36L2

1

4

High-throughput

0.479

High

820923

PRC2A
Protein PRRC2A

1

5

High-throughput

0.479

High

824007

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

843675

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.479

High

844063

FXR2
RNA-binding protein FXR2

1

4

High-throughput

0.479

High

893029

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

908542

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

963521

TIAR
Nucleolysin TIAR

1

8

High-throughput

0.479

High

966543

OTUD4
OTU domain-containing protein 4

1

3

High-throughput

0.479

High

988883

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.479

High

998709

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1017889

GRSF1
G-rich sequence factor 1

1

14

High-throughput

0.479

High

1031329

PABP4
Polyadenylate-binding protein 4

1

6

High-throughput

0.479

High

1035734

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1049026

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1049800

UBP2L
Ubiquitin-associated protein 2-like

1

3

High-throughput

0.479

High

1054313

RBM39
RNA-binding protein 39

1

9

High-throughput

0.479

High

1056651

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

High-throughput

0.479

High

1056652

R3HD1
R3H domain-containing protein 1

1

5

High-throughput

0.479

High

1056656

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

13

High-throughput

0.479

High

1056660

LSM12
Protein LSM12

1

1

High-throughput

0.479

High

1056661

GLE1
mRNA export factor GLE1

1

1

High-throughput

0.479

High

1056662

PRC2B
Protein PRRC2B

1

6

High-throughput

0.479

High

1056665

UBAP2
Ubiquitin-associated protein 2

1

5

High-throughput

0.479

High

1056666

TUT4
Terminal uridylyltransferase 4

1

4

High-throughput

0.479

High

1056669

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

1

3

High-throughput

0.479

High

1056670

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

1056671

CEP85
Centrosomal protein of 85 kDa

1

1

High-throughput

0.479

High

1056674

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1056677

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1056678

LARP4
La-related protein 4

1

3

High-throughput

0.479

High

1056679

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

1056681

NUFP2
FMR1-interacting protein NUFIP2

1

1

High-throughput

0.479

High

1056682

YTHD3
YTH domain-containing family protein 3

1

5

High-throughput

0.479

High

1056683

PATL1
Protein PAT1 homolog 1

1

2

High-throughput

0.479

High

1056685

MEX3D
RNA-binding protein MEX3D

1

6

High-throughput

0.479

High

1056686

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

3

High-throughput

0.479

High

1056688

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1056689

RAVR1
Ribonucleoprotein PTB-binding 1

1

8

High-throughput

0.479

High

1056691

RPTOR
Regulatory-associated protein of mTOR

1

2

High-throughput

0.479

High

1056698

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.479

High

1056699

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

4

High-throughput

0.479

High

1056701

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1056704

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1056705

SMAP2
Stromal membrane-associated protein 2

1

1

High-throughput

0.479

High

1056706

ATX2L
Ataxin-2-like protein

1

3

High-throughput

0.479

High

1056707

DDX1
ATP-dependent RNA helicase DDX1

1

4

High-throughput

0.479

High

1056708

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1056709

CNOT9
CCR4-NOT transcription complex subunit 9

1

5

High-throughput

0.479

High

1056711

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1056712

CELF1
CUGBP Elav-like family member 1

1

10

High-throughput

0.479

High

1056713

RENT1
Regulator of nonsense transcripts 1

1

4

High-throughput

0.479

High

1056714

DAZL
Deleted in azoospermia-like

1

11

High-throughput

0.479

High

1056716

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1056718

FUBP1
Far upstream element-binding protein 1

1

6

High-throughput

0.479

High

1056722

AURKB
Aurora kinase B

1

2

High-throughput

0.479

High

1056723

FUBP3
Far upstream element-binding protein 3

1

7

High-throughput

0.479

High

1056729

ATX2
Ataxin-2

1

3

High-throughput

0.479

High

1056731

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1056732

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

2

High-throughput

0.479

High

1056733

RIOK1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

1056734

TRI56
E3 ubiquitin-protein ligase TRIM56

1

9

High-throughput

0.479

High

1056735

MCRI2
MAPK regulated corepressor interacting protein 2

1

1

High-throughput

0.479

High

1056736

YTHD1
YTH domain-containing family protein 1

1

5

High-throughput

0.479

High

1056739

UNK
RING finger protein unkempt homolog

1

5

High-throughput

0.479

High

1056740

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

4

High-throughput

0.479

High

1056741

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

3

High-throughput

0.479

High

1056742

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1056743

SAV1
Protein salvador homolog 1

1

1

High-throughput

0.479

High

1056744

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1056745

BICC1
Protein bicaudal C homolog 1

1

12

High-throughput

0.479

High

1056749

AGO3
Protein argonaute-3

1

4

High-throughput

0.479

High

1056751

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

1056752

MOV10
Helicase MOV-10

1

4

High-throughput

0.479

High

1056753

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

6

High-throughput

0.479

High

1056754

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

3

High-throughput

0.479

High

1056755

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1056756

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1056758

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

3

High-throughput

0.479

High

1056759

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

8

High-throughput

0.479

High

1056760

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

3

High-throughput

0.479

High

1056765

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

6

High-throughput

0.479

High

1056767

CNOT2
CCR4-NOT transcription complex subunit 2

1

5

High-throughput

0.479

High

1056769

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1056770

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

3

Small-scale

0.479

High

1056771

CNOT7
CCR4-NOT transcription complex subunit 7

1

9

High-throughput

0.479

High

1056773

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.479

High

1056774

AGO2
Protein argonaute-2

1

4

High-throughput

0.479

High

1056776

AGO1
Protein argonaute-1

1

4

High-throughput

0.479

High

1056778

G3BP2
Ras GTPase-activating protein-binding protein 2

1

8

High-throughput

0.479

High

1056779

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

3

High-throughput

0.479

High

1056780

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.479

High

1056782

R3HD2
R3H domain-containing protein 2

1

4

High-throughput

0.479

High

1056783

STRAP
Serine-threonine kinase receptor-associated protein

1

2

High-throughput

0.479

High

1056784

PRC2C
Protein PRRC2C

1

6

High-throughput

0.479

High

1056785

YTHD2
YTH domain-containing family protein 2

1

5

High-throughput

0.479

High

1056786

MAGD1
Melanoma-associated antigen D1

1

3

High-throughput

0.479

High

1056787

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

6

High-throughput

0.479

High

68566

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

166235

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

268988

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.458

High

298517

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325732

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

328847

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

338438

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

409075

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

529122

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

684722

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

758232

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.458

High

961114

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1053853

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

1056655

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1056658

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1056659

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1056663

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

1056673

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1056692

ZCH24
Zinc finger CCHC domain-containing protein 24

1

0

High-throughput

0.458

High

1056695

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1056696

FA98A
Protein FAM98A

1

0

High-throughput

0.458

High

1056700

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1056702

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1056719

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1056726

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.458

High

1056746

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1056747

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1056748

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1056757

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1056761

AATF
Protein AATF

1

0

High-throughput

0.458

High

1056763

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1056775

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.458

High

70150

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

3

High-throughput

0.445

High

1056675

NBEL2
Neurobeachin-like protein 2

1

3

High-throughput

0.445

High

1056781

DICER
Endoribonuclease Dicer

1

2

Small-scale

0.445

High

795754

MAGA3
Melanoma-associated antigen 3

1

3

Small-scale

0.437

High

1056680

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1056697

RN214
RING finger protein 214

1

2

High-throughput

0.437

High

1056664

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1056668

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

1056727

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

196776

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.279

Low

1016948

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1056766

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

281625

WFS1
Wolframin

1

0

High-throughput

0.268

Low

530660

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

1056672

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1056762

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

581731

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024