HitPredict

Interactor 1: P2Y10 (O00398)
Putative P2Y purinoceptor 10 (P2Y10) (P2Y-like receptor)
Gene: P2RY10

Interactor 2: PI4KA (P42356)
Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha)
Gene: PI4KA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 2102
+	Hs
		723045 OPRM_HUMAN (1-334): 5.81e-67: 217: 21.11		Q4LE69_HUMAN (30-2102): 0: 2747: 100.00
+	Hs
		723312 APJ_HUMAN (15-335): 2.68e-67: 217: 24.70		Q4LE69_HUMAN (30-2102): 0: 2747: 100.00
+	Hs
		723014 OPRM_HUMAN (1-334): 5.81e-67: 217: 21.11		PI4KA_HUMAN (30-2102): 0: 2745: 100.00
+	Hs
		723280 APJ_HUMAN (15-335): 2.68e-67: 217: 24.70		PI4KA_HUMAN (30-2102): 0: 2745: 100.00
+	Hs
		126596 P2Y10_HUMAN (1-339): 4.36e-65: 210: 100.00		Q4LE69_HUMAN (30-2102): 0: 2747: 100.00
+	Hs
		876131 PAR2_HUMAN (19-315): 1.43e-33: 129: 29.90		Q4LE69_HUMAN (30-2102): 0: 2747: 100.00
+	Hs
		787637 PAR2_HUMAN (19-315): 1.43e-33: 129: 29.90		PI4KA_HUMAN (30-2102): 0: 2745: 100.00
+	Hs
		1117762 P2RY8_HUMAN (34-319): 4.94e-30: 119: 33.33		Q4LE69_HUMAN (30-2102): 0: 2747: 100.00
+	Hs
		787661 P2RY8_HUMAN (34-319): 4.94e-30: 119: 33.33		PI4KA_HUMAN (30-2102): 0: 2745: 100.00
+	Hs
		171954 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		PI4KA_HUMAN (30-2102): 0: 2745: 100.00
+	Hs
		787363 CXCR4_HUMAN (5-339): 2.24e-65: 212: 21.96		PK3CB_HUMAN (1555-2099): 3.14e-140: 468: 20.98
+	Hs
		126573 P2Y10_HUMAN (1-339): 4.36e-65: 210: 100.00		PK3CB_HUMAN (1555-2099): 3.14e-140: 468: 20.98
+	Hs
		822537 CXCR4_HUMAN (5-339): 2.24e-65: 212: 21.96		PK3CG_HUMAN (1503-2100): 2.11e-134: 453: 19.49
+	Mm
		936867 CXCR4_MOUSE (5-339): 3.5e-64: 208: 20.94		PK3CG_MOUSE (1503-2100): 1.28e-132: 447: 19.81
+	Hs
		1030924 GPR17_HUMAN (28-317): 1.99e-85: 264: 34.25		ATR_HUMAN (1573-2101): 8.52e-106: 381: 13.13
+	Hs
		128855 P2RY6_HUMAN (32-313): 1.85e-26: 108: 31.25		P3C2A_HUMAN (1392-2101): 1.39e-153: 521: 17.98
+	Hs
		128774 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		P3C2A_HUMAN (1392-2101): 1.39e-153: 521: 17.98
+	Hs
		723038 OPRM_HUMAN (1-334): 5.81e-67: 217: 21.11		ATR_HUMAN (1573-2101): 8.52e-106: 381: 13.13
+	Hs
		787392 LPAR5_HUMAN (13-321): 2.37e-27: 112: 29.34		PK3CB_HUMAN (1555-2099): 3.14e-140: 468: 20.98
+	Hs
		171992 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		ATR_HUMAN (1573-2101): 8.52e-106: 381: 13.13