HitPredict

Interactor 1: P2Y10 (O00398)
Putative P2Y purinoceptor 10 (P2Y10) (P2Y-like receptor)
Gene: P2RY10

Interactor 2: BIG3 (Q5TH69)
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)
Gene: ARFGEF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 2177
+	Hs
		1030949 GPR17_HUMAN (28-317): 1.99e-85: 264: 34.25		BIG3_HUMAN (1-2177): 0: 2853: 100.00
+	Hs
		1136952 LPAR4_HUMAN (29-316): 6.29e-73: 231: 32.87		BIG3_HUMAN (1-2177): 0: 2853: 100.00
+	Hs
		172032 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		BIG3_HUMAN (1-2177): 0: 2853: 100.00
+	Hs
		1031127 GPR17_HUMAN (28-317): 1.99e-85: 264: 34.25		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		1031126 GPR17_HUMAN (28-317): 1.99e-85: 264: 34.25		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Hs
		1202767 P2RY8_HUMAN (34-319): 4.94e-30: 119: 33.33		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		172310 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		BIG1_HUMAN (542-1861): 0: 883: 15.57
+	Hs
		172309 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		BIG2_HUMAN (610-1861): 0: 866: 16.05
+	Hs
		1031033 GPR17_HUMAN (28-317): 1.99e-85: 264: 34.25		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		126630 P2Y10_HUMAN (1-339): 4.36e-65: 210: 100.00		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		876169 PAR2_HUMAN (19-315): 1.43e-33: 129: 29.90		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		1202696 P2RY8_HUMAN (34-319): 4.94e-30: 119: 33.33		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69
+	Hs
		172151 GP182_HUMAN (41-316): 1.21e-21: 96.7: 27.31		GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69