Interactor 1: APAF (Q7KLI1)
Apoptosome protein Dark (Death-associated APAF1-related killer) (Drosophila Apaf-1 related killer) (Homolog of Apaf-1 and ced-4)
Gene: Dark
Interactor 2: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd
Species: Drosophila melanogaster
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.24 | 0.60 | 0.381 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned4 |
| Identification Methods | experimental interaction detection |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0006915 - apoptotic process GO:0007291 - sperm individualization |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
