Protein: APAF
Apoptosome protein Dark (Death-associated APAF1-related killer) (Drosophila Apaf-1 related killer) (Homolog of Apaf-1 and ced-4)

Gene: APAF, Dark
Organism: Drosophila melanogaster
Interactions: 6
UniProt ID: Q7KLI1

Gene Ontology (top 5):
GO:0002921 - negative regulation of humoral immune response
GO:0005198 - structural molecule activity
GO:0005524 - ATP binding
GO:0006915 - apoptotic process
GO:0007291 - sperm individualization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1267323

APAF
Apoptosome protein Dark

2

0

Small-scale

0.706

High

1267327

DRONC
Caspase Dronc

3

1

Small-scale

0.646

High

1267324

CASP8
Caspase-8

1

1

High-throughput

0.381

High

1267326

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.238

Low

1267325

Q9VH81
protein-serine/threonine phosphatase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025