HitPredict

Interactor 1: NITO (Q7KMJ6)
RNA-binding protein spenito
Gene: NITO

Interactor 2: ATX2 (Q8SWR8)
Ataxin-2 homolog (Datx2)
Gene: ATX2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0048749 - compound eye development
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 793 Dm			1 1084
+	Dm
		636400 PABP_DROME (1-324): 5.76e-33: 137: 11.70		ATX2_DROME (1-1084): 6.57e-111: 372: 100.00
+	At
		842067 PABP2_ARATH (1-310): 5.22e-37: 149: 13.50		CID4_ARATH (11-556): 2.58e-46: 178: 16.78
+	Sc
		403598 PABP_YEAST (1-303): 3.3e-36: 146: 14.73		PBP1_YEAST (17-662): 2.46e-42: 168: 13.24
+	At
		1050760 PABP5_ARATH (312-483): 3.57e-28: 123: 19.13		CID4_ARATH (11-556): 2.58e-46: 178: 16.78
+	At
		264655 PABP3_ARATH (301-483): 6.6e-28: 121: 18.04		CID4_ARATH (11-556): 2.58e-46: 178: 16.78
+	At
		1375729 PABP8_ARATH (314-479): 4.38e-27: 119: 20.79		CID4_ARATH (11-556): 2.58e-46: 178: 16.78
+	Hs
		1387881 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		ATX2_HUMAN (372-1084): 2.99e-10: 66.8: 8.28
+	Hs
		1102033 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		ATX2L_HUMAN (426-1084): 3.84e-12: 72.9: 7.28
+	Hs
		1102071 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		ATX2_HUMAN (372-1084): 2.99e-10: 66.8: 8.28
+	Hs
		550367 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		KMT2C_HUMAN (288-984): 1.55e-12: 74.4: 10.29
+	Hs
		550378 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		ATX2L_HUMAN (426-1084): 3.84e-12: 72.9: 7.28
+	Hs
		1046991 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		IF4G1_HUMAN (647-1078): 3.14e-09: 63.6: 10.78
+	Hs
		550434 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		ATX2_HUMAN (372-1084): 2.99e-10: 66.8: 8.28
+	Hs
		550242 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		IF4G1_HUMAN (647-1078): 3.14e-09: 63.6: 10.78
+	Hs
		1090285 ELAV2_HUMAN (281-493): 7.6e-22: 99.8: 19.31		ATX2_HUMAN (372-1084): 2.99e-10: 66.8: 8.28