HitPredict

Interactor 1: NITO (Q7KMJ6)
RNA-binding protein spenito
Gene: NITO

Interactor 2: Q9VYD8 (Q9VYD8)
RE47308p (Rbp1-like, isoform A) (Rbp1-like, isoform C)
Gene: Rbp1-like

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0000398 - mRNA splicing, via spliceosome GO:0003729 - mRNA binding GO:0071011 - precatalytic spliceosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 793 Dm			1 158
+	Dm
		1267521 NITO_DROME (1-793): 5.1e-151: 462: 100.00		LARK_DROME (9-86): 7.12e-12: 63.7: 26.92
+	Hs
		506125 PAB4L_HUMAN (1-269): 3.45e-40: 153: 11.93		SRSF3_HUMAN (5-152): 2.13e-28: 104: 45.27
+	Hs
		506129 PAB4L_HUMAN (1-269): 3.45e-40: 153: 11.93		PABP4_HUMAN (1-89): 4.02e-21: 90.7: 22.92
+	Hs
		1061087 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		SRSF1_HUMAN (10-82): 3.84e-24: 95.5: 49.33
+	Hs
		1102056 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		PABP4_HUMAN (1-89): 4.02e-21: 90.7: 22.92
+	Sc
		403283 PABP_YEAST (1-303): 3.3e-36: 146: 14.73		PABP_YEAST (3-95): 1.2e-18: 83.3: 22.45
+	Hs
		550407 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		PABP1_HUMAN (12-157): 1.32e-20: 89.1: 18.12
+	Hs
		1197174 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		PAP1L_HUMAN (12-96): 4.02e-20: 87.6: 22.73
+	Hs
		911574 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		NCBP2_HUMAN (10-116): 3.28e-26: 98.8: 30.36
+	Hs
		1099010 PABP5_HUMAN (1-284): 3.31e-35: 140: 12.33		SRSF9_HUMAN (8-83): 6.3e-19: 81.3: 38.46
+	Hs
		550190 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		NCBP2_HUMAN (10-116): 3.28e-26: 98.8: 30.36
+	Hs
		550262 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		PABP1_HUMAN (12-157): 1.32e-20: 89.1: 18.12
+	Hs
		1102095 PABP4_HUMAN (14-242): 6.89e-30: 128: 12.03		PABP3_HUMAN (12-157): 5.12e-19: 84.5: 18.79
+	Hs
		550311 PAP1L_HUMAN (14-295): 9.02e-28: 121: 10.92		PABP1_HUMAN (12-157): 1.32e-20: 89.1: 18.12
+	Hs
		550464 PABP3_HUMAN (304-486): 7.84e-28: 121: 20.10		PABP1_HUMAN (12-157): 1.32e-20: 89.1: 18.12
+	Hs
		550097 PABP1_HUMAN (14-310): 1.25e-27: 120: 11.58		PABP1_HUMAN (12-157): 1.32e-20: 89.1: 18.12
+	Hs
		1197178 PABP3_HUMAN (304-486): 7.84e-28: 121: 20.10		PAP1L_HUMAN (12-96): 4.02e-20: 87.6: 22.73
+	Mm
		710979 PABP1_MOUSE (14-310): 5.34e-28: 121: 11.58		TIA1_MOUSE (6-96): 6.01e-18: 81: 25.53