Interactor 1: EDEM1 (Q92611)
ER degradation-enhancing alpha-mannosidase-like protein 1
Gene: EDEM1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 32423001
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0036503 - ERAD pathway
GO:0051787 - misfolded protein binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 657
Hs

1 303
+ Hs
+ Hs

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Last updated: 15 Jul 2024