HitPredict

Interactor 1: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2054 Hs			1 2365
+	Hs
		1167392 MY18A_HUMAN (1-2054): 0: 1279: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		724943 MY18A_HUMAN (1-2054): 0: 1279: 100.00		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		1068617 MY18A_HUMAN (1-2054): 0: 1279: 100.00		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		108763 MY18A_HUMAN (1-2054): 0: 1279: 100.00		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Dm
		1303383 MYO7A_DROME (347-1359): 0: 824: 21.39		MYSN_DROME (1678-2364): 1.82e-45: 184: 12.70
+	Hs
		725013 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		724884 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		528432 MYH8_HUMAN (1116-1997): 2.71e-53: 209: 14.76		MYH13_HUMAN (1524-2365): 2.97e-45: 183: 8.91
+	Hs
		528356 MYH6_HUMAN (1141-2053): 1.27e-51: 204: 13.34		MYH6_HUMAN (1655-2365): 7.59e-43: 175: 10.13
+	Hs
		502901 MYH3_HUMAN (1134-2052): 4.44e-51: 202: 15.52		MYH6_HUMAN (1655-2365): 7.59e-43: 175: 10.13
+	Dm
		1303379 MYSN_DROME (1218-1932): 2.19e-38: 160: 23.06		MYSN_DROME (1678-2364): 1.82e-45: 184: 12.70
+	Rn
		361106 MYH6_RAT (956-1858): 6.36e-41: 168: 13.00		MYH6_RAT (1655-2365): 5.46e-43: 176: 9.99
+	Hs
		522585 MYH7_HUMAN (954-1819): 2.95e-41: 169: 12.80		MYH7_HUMAN (1667-2364): 7.9e-42: 172: 10.69
+	Hs
		724686 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		724687 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Mm
		93570 MYH9_MOUSE (1173-2014): 1.03e-51: 204: 16.16		DESP_MOUSE (1531-2365): 5.7e-16: 87.3: 9.76
+	Hs
		724839 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		724895 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		108759 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Hs
		724782 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82