Protein: SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)

Gene: SUCA, SUCLG1
Organism: Homo sapiens
Interactions: 77
UniProt ID: P53597

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0003723 - RNA binding
GO:0004775 - succinate-CoA ligase (ADP-forming) activity
GO:0004776 - succinate-CoA ligase (GDP-forming) activity
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921451

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

4

8

Small-scale

0.899

High

921464

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

8

High-throughput

0.811

High

921434

SYAM
Alanine--tRNA ligase, mitochondrial

2

2

High-throughput

0.628

High

279707

CISY
Citrate synthase, mitochondrial

1

5

High-throughput

0.618

High

921428

SYLM
Leucine--tRNA ligase, mitochondrial

2

0

High-throughput

0.602

High

400526

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.584

High

921432

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

371546

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.549

High

348433

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.536

High

529401

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

921442

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.530

High

921445

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.521

High

921456

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

507714

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

921462

SMYD2
N-lysine methyltransferase SMYD2

1

1

High-throughput

0.489

High

921443

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.481

High

921448

WDR36
WD repeat-containing protein 36

1

1

High-throughput

0.481

High

241176

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

472547

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

532475

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

534821

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

536812

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

786037

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

828717

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

921425

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

921426

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

4

High-throughput

0.479

High

921431

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

921446

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

921460

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

921438

CHM1B
Charged multivesicular body protein 1b

1

1

High-throughput

0.464

High

851853

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

921421

VIGLN
Vigilin

1

0

High-throughput

0.458

High

921423

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

921424

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

921436

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

921450

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

921454

TR61B
tRNA

1

0

High-throughput

0.458

High

921463

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

921435

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

227447

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.437

High

606486

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.437

High

764570

CTNB1
Catenin beta-1

1

1

High-throughput

0.437

High

878825

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

921417

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.437

High

921418

HDAC4
Histone deacetylase 4

1

2

High-throughput

0.437

High

921419

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

921422

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

921427

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.437

High

921429

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.437

High

921430

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

921437

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

921439

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

921440

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

Small-scale

0.437

High

921444

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.437

High

921447

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.437

High

921449

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.437

High

921452

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

921457

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.437

High

921458

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

921461

ECT2
Protein ECT2

1

1

High-throughput

0.437

High

921465

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

653212

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

97236

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

457328

TBB5
Tubulin beta chain

1

2

High-throughput

0.407

High

921466

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.407

High

369251

ANT3
Antithrombin-III

3

0

High-throughput

0.347

High

921453

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.328

High

921455

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

332090

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.249

Low

342138

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

659191

SP100
Nuclear autoantigen Sp-100

1

0

High-throughput

0.249

Low

897175

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.249

Low

921420

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

921433

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

921441

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.249

Low

921459

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

397920

ANGI
Angiogenin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025