Interactor 1: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1
Interactor 2: E2AK4 (Q9P2K8)
eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 4) (GCN2-like protein)
Gene: EIF2AK4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 0.60 | 0.479 |
The method score is based on:
Property | Details |
---|---|
Experiments | 36638793 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0022626 - cytosolic ribosome GO:0034198 - cellular response to amino acid starvation GO:0140469 - GCN2-mediated signaling |
Homologous interactions | 6 |
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Last updated: 15 Jul 2024