Protein: Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase, isoform D)

Gene: Q7KN99, Ppcs
Organism: Drosophila melanogaster
Interactions: 144
UniProt ID: Q7KN99

Gene Ontology (top 5):
GO:0004632 - phosphopantothenate--cysteine ligase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0015937 - coenzyme A biosynthetic process
GO:0055091 - phospholipid homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1268234

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

2

2

High-throughput

0.767

High

1268268

Q9VCH9
LD07883p

2

0

High-throughput

0.569

High

1268308

Q9VX82
Actin-related protein 2/3 complex subunit 3

2

0

High-throughput

0.569

High

95286

E1JII8
Uncharacterized protein, isoform C

1

1

High-throughput

0.494

High

1268276

Q9VGL1
IP21116p

1

1

High-throughput

0.481

High

1268312

Q9VYD9
alanine transaminase

1

1

High-throughput

0.451

High

57569

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.445

High

871622

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

3

High-throughput

0.445

High

929493

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.445

High

1019594

TRXR1
Thioredoxin reductase 1, mitochondrial

1

1

High-throughput

0.445

High

1176530

NLP
Nucleoplasmin-like protein

1

1

High-throughput

0.445

High

1268258

THIO2
Thioredoxin-2

1

1

High-throughput

0.445

High

1268260

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.445

High

1268263

Q9VAC4
GEO09167p1

1

1

High-throughput

0.445

High

1268287

FKB59
FK506-binding protein 59

1

2

High-throughput

0.445

High

1268290

PSB4
Proteasome subunit beta type-4

1

1

High-throughput

0.445

High

1268299

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.445

High

1268311

CLIC
Chloride intracellular channel Clic

1

1

High-throughput

0.445

High

1268324

PSB3
Proteasome subunit beta type-3

1

1

High-throughput

0.445

High

1268325

Q9XYZ9
Glutathione S transferase E12, isoform A

1

1

High-throughput

0.445

High

1268327

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.445

High

1268236

Q7KV27
alanine transaminase

1

1

High-throughput

0.439

High

57790

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.426

High

121618

M9PFR6
Multiprotein bridging factor 1, isoform E

1

0

High-throughput

0.426

High

195040

O16043
Anon1A4

1

0

High-throughput

0.426

High

305201

TRMB
tRNA

1

0

High-throughput

0.426

High

305661

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

356351

O97102
Small ubiquitin-related modifier

1

0

High-throughput

0.426

High

357515

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.426

High

556686

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.426

High

578087

ENO
Enolase

1

0

High-throughput

0.426

High

609399

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.426

High

649050

ANX10
Annexin B10

1

0

High-throughput

0.426

High

682754

PROF
Profilin

1

0

High-throughput

0.426

High

762556

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

0

High-throughput

0.426

High

856020

MOEH
Moesin/ezrin/radixin homolog 1

1

0

High-throughput

0.426

High

928968

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

1019867

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.426

High

1260805

Q76NR6
Regucalcin

1

0

High-throughput

0.426

High

1262980

Q7JXC4
CG6459 protein

1

0

High-throughput

0.426

High

1264653

Q7K148
Proteasome subunit beta

1

0

High-throughput

0.426

High

1267878

TERA
Transitional endoplasmic reticulum ATPase TER94

1

0

High-throughput

0.426

High

1268235

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.426

High

1268237

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

1268238

Q8IQZ7
FI19014p1

1

0

High-throughput

0.426

High

1268240

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

1268241

Q8MYY7
RE44624p

1

0

High-throughput

0.426

High

1268242

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.426

High

1268243

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.426

High

1268244

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

1268245

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

1268247

FAXC
Failed axon connections

1

0

High-throughput

0.426

High

1268248

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.426

High

1268249

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

1268250

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.426

High

1268251

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.426

High

1268252

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.426

High

1268254

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

1268256

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.426

High

1268257

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.426

High

1268261

Q9V9U3
LD45254p

1

0

High-throughput

0.426

High

1268272

Q9VEB1
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

1268277

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.426

High

1268278

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

1268282

Q9VKB0
threonine--tRNA ligase

1

0

High-throughput

0.426

High

1268288

AK200
A-kinase anchor protein 200

1

0

High-throughput

0.426

High

1268293

Q9VPN5
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.426

High

1268294

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.426

High

1268295

BACC
Bacchus

1

0

High-throughput

0.426

High

1268296

Q9VRD6
NTF2-related export protein

1

0

High-throughput

0.426

High

1268297

Q9VRL1
GEO06356p1

1

0

High-throughput

0.426

High

1268302

Q9VUC1
Hsc70Cb, isoform A

1

0

High-throughput

0.426

High

1268303

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.426

High

1268307

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.426

High

1268315

Q9W0H8
Reticulocalbin-3

1

0

High-throughput

0.426

High

1268316

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

1268317

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

1268319

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.426

High

1268321

WUHO
tRNA

1

0

High-throughput

0.426

High

1268322

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

1268326

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.426

High

1268328

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.426

High

1268331

Q9Y170
Sex-regulated protein janus-B

1

0

High-throughput

0.426

High

54014

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

121239

ALDR
Aldo-keto reductase 1B

1

4

High-throughput

0.407

High

1191649

Q3YMU0
Protein disulfide-isomerase

1

1

High-throughput

0.407

High

1262120

Q7JVH6
LD24696p

1

4

High-throughput

0.407

High

1262804

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

1268255

Q9V3V2
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

1268259

PDIA6
Protein disulfide-isomerase A6 homolog

1

1

High-throughput

0.407

High

1268275

Q9VGK3
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

1268280

Q9VHX4
LD24679p

1

4

High-throughput

0.407

High

1268300

Q9VTY2
Uncharacterized protein, isoform A

1

4

High-throughput

0.407

High

1268304

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

1268314

Q9W022
GEO01508p1

1

2

High-throughput

0.407

High

1268329

Q9Y112
BcDNA.GH10614

1

4

High-throughput

0.407

High

86501

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.232

Low

197783

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.232

Low

304633

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.232

Low

357298

O97428
Ciboulot, isoform A

1

0

High-throughput

0.232

Low

460058

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

476952

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low

712352

CALR
Calreticulin

1

0

High-throughput

0.232

Low

821849

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.232

Low

874654

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.232

Low

930149

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

1031195

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

1052406

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

1070757

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

1265231

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

1268239

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.232

Low

1268246

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

1268253

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.232

Low

1268262

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

1268264

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.232

Low

1268265

Q9VAY2
Heat shock protein 83

1

0

High-throughput

0.232

Low

1268266

Q9VBR6
RE74917p

1

0

High-throughput

0.232

Low

1268267

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1268269

Q9VCK6
LD34157p

1

0

High-throughput

0.232

Low

1268270

Q9VD02
GH14779p

1

0

High-throughput

0.232

Low

1268271

Q9VD29
small monomeric GTPase

1

0

High-throughput

0.232

Low

1268273

FLNA
Filamin-A

1

0

High-throughput

0.232

Low

1268274

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

1268279

Q9VHN7
transketolase

1

0

High-throughput

0.232

Low

1268281

Q9VIE8
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.232

Low

1268283

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.232

Low

1268284

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

1268285

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

0

High-throughput

0.232

Low

1268286

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

1268289

Q9VMU6
LD31822p

1

0

High-throughput

0.232

Low

1268291

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

1268292

Q9VP52
GH24315p

1

0

High-throughput

0.232

Low

1268298

Q9VRP2
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1268301

Q9VU35
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

1268305

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.232

Low

1268306

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

1268309

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

1268310

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.232

Low

1268313

Q9VZI1
Transgelin

1

0

High-throughput

0.232

Low

1268318

Q9W3X6
fumarate hydratase

1

0

High-throughput

0.232

Low

1268320

CISY
Probable citrate synthase, mitochondrial

1

0

High-throughput

0.232

Low

1268323

Q9W478
RE43153p

1

0

High-throughput

0.232

Low

1268330

DHRS7
Dehydrogenase/reductase SDR family protein 7-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025