HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 888
+	Hs
		203191 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		VINEX_HUMAN (245-888): 2.14e-32: 136: 13.37
+	Rn
		192744 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SRBS2_RAT (428-502): 9.43e-23: 106: 44.32
+	Rn
		192356 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G3_RAT (789-888): 1.67e-18: 89.9: 27.00
+	Hs
		203192 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Rn
		193638 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G1_RAT (234-509): 5.55e-16: 82.6: 13.41
+	Rn
		192354 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G2_RAT (371-504): 6.4e-15: 79.1: 19.40
+	Mm
		88460 D3Z656_MOUSE (4-505): 5.91e-61: 218: 13.01		SH3G3_MOUSE (789-888): 1.53e-17: 87.2: 26.00
+	Hs
		203248 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3G1_HUMAN (234-509): 1.3e-15: 81.4: 12.68
+	Hs
		203250 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		203246 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3Y1_HUMAN (734-885): 2.77e-14: 77.2: 16.23
+	Hs
		203249 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3G2_HUMAN (371-504): 2.89e-14: 77.2: 17.91
+	Hs
		203230 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		166056 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN2_HUMAN (117-266): 1.18e-14: 81: 18.99
+	Mm
		88459 D3Z656_MOUSE (4-505): 5.91e-61: 218: 13.01		SH3G2_MOUSE (371-504): 1.82e-14: 78: 18.66
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (551-888): 1.75e-12: 73.7: 12.83
+	Hs
		276974 SC31A_HUMAN (10-495): 1.62e-51: 191: 10.39		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (551-888): 1.75e-12: 73.7: 12.83
+	Hs
		166060 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		CD2AP_HUMAN (764-888): 1.62e-12: 73.3: 30.47
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (125-235): 2.87e-13: 76: 23.42
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (610-888): 1.71e-12: 73.7: 14.29