HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: PABP3 (Q9H361)
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)
Gene: PABPC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	21182203, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 631
+	Hs
		1031409 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		368886 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		370422 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PABP3_HUMAN (1-631): 0: 565: 100.00
+	Hs
		1119140 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PAP1L_HUMAN (1-623): 9.42e-165: 486: 64.97
+	Hs
		369534 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		369739 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PAP1L_HUMAN (1-623): 9.42e-165: 486: 64.97
+	Mm
		509289 RARA_MOUSE (52-508): 5.87e-105: 324: 23.58		PABP1_MOUSE (1-631): 0: 572: 91.68
+	Hs
		516359 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		782537 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		611434 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		PABP4_HUMAN (1-630): 0: 531: 69.60
+	Hs
		487081 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		PABP1_HUMAN (1-631): 0: 573: 91.99
+	Hs
		1269332 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16
+	Hs
		370176 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PABP5_HUMAN (6-179): 8.16e-39: 149: 23.16
+	Hs
		582413 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82
+	Hs
		680471 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TIA1_HUMAN (288-376): 7.36e-12: 69.3: 24.72
+	Hs
		368961 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82
+	Hs
		369064 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TIA1_HUMAN (288-376): 7.36e-12: 69.3: 24.72
+	Hs
		377077 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		NUCL_HUMAN (2-89): 4.1e-19: 93.7: 31.82