HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: COPG2 (Q9UBF2)
Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)
Gene: COPG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.569

Property	Details
Experiments	29509190, 21182203, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 871
+	Hs
		1270046 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		COPG1_HUMAN (1-871): 0: 844: 80.44
+	Hs
		370619 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		COPG2_HUMAN (1-871): 0: 869: 100.00
+	Hs
		370827 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		COPG1_HUMAN (1-871): 0: 844: 80.44
+	Hs
		321608 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		AP2A1_HUMAN (24-871): 0: 567: 14.88
+	Hs
		302191 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		AP2A2_HUMAN (24-871): 1.93e-180: 546: 15.30
+	Hs
		925963 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		AP2B1_HUMAN (14-600): 2.1e-176: 535: 14.45
+	Hs
		321456 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		AP2A1_HUMAN (24-871): 0: 567: 14.88
+	Hs
		212652 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		AP1G1_HUMAN (20-738): 1.94e-170: 516: 15.07
+	Hs
		302083 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		AP2A2_HUMAN (24-871): 1.93e-180: 546: 15.30
+	Hs
		369353 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		AP2B1_HUMAN (14-600): 2.1e-176: 535: 14.45
+	Hs
		212582 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		AP1G1_HUMAN (20-738): 1.94e-170: 516: 15.07
+	Mm
		509283 RARA_MOUSE (52-508): 5.87e-105: 324: 23.58		AP2A1_MOUSE (24-871): 0: 571: 14.67
+	Mm
		509284 RARA_MOUSE (52-508): 5.87e-105: 324: 23.58		AP2A2_MOUSE (24-871): 0: 559: 15.32
+	Hs
		377279 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		AP1B1_HUMAN (14-638): 2.54e-177: 538: 14.84
+	Mm
		509347 RARA_MOUSE (52-508): 5.87e-105: 324: 23.58		AP2B1_MOUSE (14-600): 1.97e-176: 535: 14.45