HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	19686092, 23752268, 15016378
Identification Methods	affinity chromatography technology, pull down, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 709
+	Hs
		1038800 HDAC1_HUMAN (1-443): 0: 642: 90.07		DP13A_HUMAN (1-709): 0: 663: 100.00
+	Hs
		177401 HDAC3_HUMAN (10-431): 0: 574: 58.26		DP13A_HUMAN (1-709): 0: 663: 100.00
+	Mm
		1157789 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		OPHN1_MOUSE (3-427): 3.46e-103: 335: 17.55
+	Hs
		1064308 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		ACAP1_HUMAN (6-449): 1.25e-106: 343: 17.92