HitPredict

Interactor 1: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36537216
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2004 Hs			1 504
+	Hs
		1270865 KAT6A_HUMAN (1-2004): 0: 1040: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		903406 KAT6A_HUMAN (1-2004): 0: 1040: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1074802 KAT6A_HUMAN (1-2004): 0: 1040: 100.00		TAF5_HUMAN (233-434): 3.88e-16: 83.6: 26.60
+	Hs
		1018750 CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		309726 KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1059942 CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13		PRP19_HUMAN (1-504): 2.85e-165: 479: 100.00
+	Hs
		903522 KAT8_HUMAN (357-789): 2.81e-138: 441: 37.73		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Sc
		692368 ESA1_YEAST (378-787): 2.7e-150: 474: 36.36		PRP19_YEAST (3-138): 1.03e-22: 103: 38.19
+	Dm
		137457 MOF_DROME (401-782): 6.63e-111: 376: 36.98		WDS_DROME (93-337): 9.07e-43: 157: 15.23
+	Hs
		1018633 CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Sc
		630897 MDN1_YEAST (1014-1648): 5.68e-46: 186: 15.52		NLE1_YEAST (169-503): 1.51e-84: 272: 19.44
+	Hs
		197011 CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		1059779 CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1018714 CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		197020 CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		1259960 PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		903234 CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1056932 MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		152622 KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Dm
		836169 SAYP_DROME (197-310): 8.15e-33: 142: 34.21		TAF5_DROME (218-504): 3.33e-09: 61.2: 21.48