Protein: RHOV
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)

Gene: RHOV
Organism: Homo sapiens
Interactions: 239
UniProt ID: Q96L33

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0007015 - actin filament organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354757

PAK4
Serine/threonine-protein kinase PAK 4

2

20

High-throughput

0.754

High

1396637

PAK6
Serine/threonine-protein kinase PAK 6

2

20

High-throughput

0.700

High

133684

WASL
Actin nucleation-promoting factor WASL

1

20

High-throughput

0.618

High

135980

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

20

High-throughput

0.618

High

254206

CTND1
Catenin delta-1

1

20

High-throughput

0.618

High

324362

SLIK5
SLIT and NTRK-like protein 5

1

20

High-throughput

0.618

High

363725

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

463197

YES
Tyrosine-protein kinase Yes

1

20

High-throughput

0.618

High

577860

PLAK
Junction plakoglobin

1

20

High-throughput

0.618

High

692117

MARK3
MAP/microtubule affinity-regulating kinase 3

1

20

High-throughput

0.618

High

699830

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

710432

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

783643

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

18

High-throughput

0.618

High

835731

KPCI
Protein kinase C iota type

1

20

High-throughput

0.618

High

839343

MTOR
Serine/threonine-protein kinase mTOR

1

20

High-throughput

0.618

High

845758

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.618

High

857537

NOTC1
Neurogenic locus notch homolog protein 1

1

20

High-throughput

0.618

High

862941

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

20

High-throughput

0.618

High

902009

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.618

High

908161

KS6A3
Ribosomal protein S6 kinase alpha-3

1

12

High-throughput

0.618

High

955481

CDC42
Cell division control protein 42 homolog

1

18

High-throughput

0.618

High

1004165

CXAR
Coxsackievirus and adenovirus receptor

1

20

High-throughput

0.618

High

1025832

BORG5
Cdc42 effector protein 1

1

20

High-throughput

0.618

High

1034321

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

18

High-throughput

0.618

High

1047701

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.618

High

1051038

FAK1
Focal adhesion kinase 1

1

20

High-throughput

0.618

High

1090073

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.618

High

1091557

DLG1
Disks large homolog 1

1

20

High-throughput

0.618

High

1096479

PAK1
Serine/threonine-protein kinase PAK 1

1

20

High-throughput

0.618

High

1097225

PAK2
Serine/threonine-protein kinase PAK 2

1

20

High-throughput

0.618

High

1104461

ILK
Scaffold protein ILK

1

17

High-throughput

0.618

High

1118385

BMPR2
Bone morphogenetic protein receptor type-2

1

20

High-throughput

0.618

High

1121972

ARHG7
Rho guanine nucleotide exchange factor 7

1

20

High-throughput

0.618

High

1122311

SCRIB
Protein scribble homolog

1

20

High-throughput

0.618

High

1129068

RASA3
Ras GTPase-activating protein 3

1

20

High-throughput

0.618

High

1143120

PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

1

15

High-throughput

0.618

High

1157548

PKN2
Serine/threonine-protein kinase N2

1

20

High-throughput

0.618

High

1216015

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

20

High-throughput

0.618

High

1270496

MARK2
Serine/threonine-protein kinase MARK2

1

20

High-throughput

0.618

High

1309585

SLIK4
SLIT and NTRK-like protein 4

1

20

High-throughput

0.618

High

1311211

RHG12
Rho GTPase-activating protein 12

1

20

High-throughput

0.618

High

1351379

DLG5
Disks large homolog 5

1

20

High-throughput

0.618

High

1353245

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.618

High

1382764

FERM2
Fermitin family homolog 2

1

12

High-throughput

0.618

High

1396619

PKP4
Plakophilin-4

1

20

High-throughput

0.618

High

1396620

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

4

High-throughput

0.618

High

1396621

PAR6B
Partitioning defective 6 homolog beta

1

20

High-throughput

0.618

High

1396626

BORG4
Cdc42 effector protein 4

1

20

High-throughput

0.618

High

1396632

PKHA1
Pleckstrin homology domain-containing family A member 1

1

20

High-throughput

0.618

High

1396633

E41L5
Band 4.1-like protein 5

1

20

High-throughput

0.618

High

1396636

NECT3
Nectin-3

1

20

High-throughput

0.618

High

1396652

NGAP
Ras GTPase-activating protein nGAP

1

20

High-throughput

0.618

High

1396664

DAAM1
Disheveled-associated activator of morphogenesis 1

1

20

High-throughput

0.618

High

1396666

MYO5A
Unconventional myosin-Va

1

6

High-throughput

0.618

High

1396668

MRCKB
Serine/threonine-protein kinase MRCK beta

1

20

High-throughput

0.618

High

1396673

ROBO1
Roundabout homolog 1

1

11

High-throughput

0.618

High

222177

NCK2
Cytoplasmic protein NCK2

2

20

Small-scale

0.611

High

74054

MYO9A
Unconventional myosin-IXa

1

18

High-throughput

0.553

High

134125

IPO5
Importin-5

1

9

High-throughput

0.553

High

220968

XPOT
Exportin-T

1

10

High-throughput

0.553

High

344423

TBCD8
TBC1 domain family member 8

1

17

High-throughput

0.553

High

934142

XPO2
Exportin-2

1

20

High-throughput

0.553

High

986638

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

11

High-throughput

0.553

High

1122429

GIT2
ARF GTPase-activating protein GIT2

1

20

High-throughput

0.553

High

1140191

ARHG6
Rho guanine nucleotide exchange factor 6

1

20

High-throughput

0.553

High

1195679

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

20

High-throughput

0.553

High

1217552

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

20

High-throughput

0.553

High

1231951

MRCKG
Serine/threonine-protein kinase MRCK gamma

1

20

High-throughput

0.553

High

1272194

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

18

High-throughput

0.553

High

1290470

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

20

High-throughput

0.553

High

1312042

DJC10
DnaJ homolog subfamily C member 10

1

2

High-throughput

0.553

High

1357406

DEP1B
DEP domain-containing protein 1B

1

20

High-throughput

0.553

High

1396628

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

20

High-throughput

0.553

High

1396630

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.553

High

1396631

XPO5
Exportin-5

1

15

High-throughput

0.553

High

1396654

KDIS
Kinase D-interacting substrate of 220 kDa

1

16

High-throughput

0.553

High

1396659

ANR26
Ankyrin repeat domain-containing protein 26

1

20

High-throughput

0.553

High

1396663

GIT1
ARF GTPase-activating protein GIT1

1

20

High-throughput

0.553

High

1396665

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

20

High-throughput

0.553

High

123804

MYO1C
Unconventional myosin-Ic

1

20

High-throughput

0.479

High

124090

SNP23
Synaptosomal-associated protein 23

1

18

High-throughput

0.479

High

163347

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

20

High-throughput

0.479

High

167758

PCD17
Protocadherin-17

1

12

High-throughput

0.479

High

177583

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

5

High-throughput

0.479

High

192298

YKT6
Synaptobrevin homolog YKT6

1

20

High-throughput

0.479

High

227947

MYO1B
Unconventional myosin-Ib

1

20

High-throughput

0.479

High

250136

ADCY9
Adenylate cyclase type 9

1

9

High-throughput

0.479

High

270391

WDR1
WD repeat-containing protein 1

1

7

High-throughput

0.479

High

277781

H2AY
Core histone macro-H2A.1

1

4

High-throughput

0.479

High

291120

UTP20
Small subunit processome component 20 homolog

1

6

High-throughput

0.479

High

299334

FLOT1
Flotillin-1

1

20

High-throughput

0.479

High

390733

TFR1
Transferrin receptor protein 1

1

9

High-throughput

0.479

High

409473

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

17

High-throughput

0.479

High

431878

ITB1
Integrin beta-1

1

20

High-throughput

0.479

High

447837

TPM3
Tropomyosin alpha-3 chain

1

9

High-throughput

0.479

High

448061

ITAV
Integrin alpha-V

1

20

High-throughput

0.479

High

467581

4F2
Amino acid transporter heavy chain SLC3A2

1

9

High-throughput

0.479

High

467947

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

9

High-throughput

0.479

High

482953

TPM1
Tropomyosin alpha-1 chain

1

18

High-throughput

0.479

High

538661

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

18

High-throughput

0.479

High

591345

CD44
CD44 antigen

1

16

High-throughput

0.479

High

594081

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

627392

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

20

High-throughput

0.479

High

690349

STOM
Stomatin

1

20

High-throughput

0.479

High

715724

MARCS
Myristoylated alanine-rich C-kinase substrate

1

20

High-throughput

0.479

High

722582

CTR1
High affinity cationic amino acid transporter 1

1

20

High-throughput

0.479

High

753838

MRP1
Multidrug resistance-associated protein 1

1

20

High-throughput

0.479

High

774564

BASI
Basigin

1

20

High-throughput

0.479

High

842834

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

20

High-throughput

0.479

High

863536

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

14

High-throughput

0.479

High

869653

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

20

High-throughput

0.479

High

878075

AGRE5
Adhesion G protein-coupled receptor E5

1

20

High-throughput

0.479

High

889326

NUMB
Protein numb homolog

1

20

High-throughput

0.479

High

933464

S12A2
Solute carrier family 12 member 2

1

20

High-throughput

0.479

High

989773

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

20

High-throughput

0.479

High

995463

TPM4
Tropomyosin alpha-4 chain

1

12

High-throughput

0.479

High

1007369

OLR1
Oxidized low-density lipoprotein receptor 1

1

14

High-throughput

0.479

High

1010352

BASP1
Brain acid soluble protein 1

1

20

High-throughput

0.479

High

1026181

CLH1
Clathrin heavy chain 1

1

11

High-throughput

0.479

High

1028847

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.479

High

1031845

LAT1
Large neutral amino acids transporter small subunit 1

1

20

High-throughput

0.479

High

1032525

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

9

High-throughput

0.479

High

1037028

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

1039552

TOP2B
DNA topoisomerase 2-beta

1

8

High-throughput

0.479

High

1041232

CAV1
Caveolin-1

1

11

High-throughput

0.479

High

1091710

MYO1E
Unconventional myosin-Ie

1

20

High-throughput

0.479

High

1095580

LIPA1
Liprin-alpha-1

1

20

High-throughput

0.479

High

1105234

S39A6
Zinc transporter ZIP6

1

20

High-throughput

0.479

High

1107598

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

16

High-throughput

0.479

High

1117445

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.479

High

1120797

DSG2
Desmoglein-2

1

20

High-throughput

0.479

High

1122035

EFR3A
Protein EFR3 homolog A

1

16

High-throughput

0.479

High

1124888

FLOT2
Flotillin-2

1

20

High-throughput

0.479

High

1139539

S39AE
Metal cation symporter ZIP14

1

20

High-throughput

0.479

High

1146330

L2GL1
Lethal(2) giant larvae protein homolog 1

1

13

High-throughput

0.479

High

1152595

ELAV1
ELAV-like protein 1

1

2

High-throughput

0.479

High

1153305

AAAT
Neutral amino acid transporter B(0)

1

14

High-throughput

0.479

High

1154713

VAMP3
Vesicle-associated membrane protein 3

1

20

High-throughput

0.479

High

1159804

OCLN
Occludin

1

12

High-throughput

0.479

High

1191465

GRDN
Girdin

1

20

High-throughput

0.479

High

1201033

ACTBL
Beta-actin-like protein 2

1

8

High-throughput

0.479

High

1211708

FA83B
Protein FAM83B

1

9

High-throughput

0.479

High

1225906

STEA3
Metalloreductase STEAP3

1

9

High-throughput

0.479

High

1233420

LTOR1
Ragulator complex protein LAMTOR1

1

10

High-throughput

0.479

High

1239914

CAVN1
Caveolae-associated protein 1

1

9

High-throughput

0.479

High

1246934

RICTR
Rapamycin-insensitive companion of mTOR

1

10

High-throughput

0.479

High

1292184

LIPB1
Liprin-beta-1

1

20

High-throughput

0.479

High

1293283

LSR
Lipolysis-stimulated lipoprotein receptor

1

9

High-throughput

0.479

High

1295343

CPNE8
Copine-8

1

11

High-throughput

0.479

High

1324725

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

9

High-throughput

0.479

High

1346617

VANG1
Vang-like protein 1

1

19

High-throughput

0.479

High

1349818

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

14

High-throughput

0.479

High

1394671

KIRR1
Kin of IRRE-like protein 1

1

16

High-throughput

0.479

High

1396615

S38A2
Sodium-coupled neutral amino acid symporter 2

1

20

High-throughput

0.479

High

1396616

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

10

High-throughput

0.479

High

1396622

ZDHC5
Palmitoyltransferase ZDHHC5

1

20

High-throughput

0.479

High

1396623

CCDC8
Coiled-coil domain-containing protein 8

1

9

High-throughput

0.479

High

1396624

S38A1
Sodium-coupled neutral amino acid symporter 1

1

20

High-throughput

0.479

High

1396625

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

20

High-throughput

0.479

High

1396627

MUC13
Mucin-13

1

9

High-throughput

0.479

High

1396634

JPH1
Junctophilin-1

1

20

High-throughput

0.479

High

1396635

WDR6
tRNA

1

16

High-throughput

0.479

High

1396643

TMOD3
Tropomodulin-3

1

10

High-throughput

0.479

High

1396645

MYOF
Myoferlin

1

20

High-throughput

0.479

High

1396646

EHD2
EH domain-containing protein 2

1

18

High-throughput

0.479

High

1396647

HACD3
Very-long-chain

1

8

High-throughput

0.479

High

1396648

SH3B4
SH3 domain-binding protein 4

1

9

High-throughput

0.479

High

1396649

SEP10
Septin-10

1

15

High-throughput

0.479

High

1396650

S53A1
Solute carrier family 53 member 1

1

9

High-throughput

0.479

High

1396653

S39AA
Zinc transporter ZIP10

1

20

High-throughput

0.479

High

1396655

VANG2
Vang-like protein 2

1

19

High-throughput

0.479

High

1396657

MYO6
Unconventional myosin-VI

1

15

High-throughput

0.479

High

1396658

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

20

High-throughput

0.479

High

1396660

XCT
Cystine/glutamate transporter

1

20

High-throughput

0.479

High

1396661

BAIP2
BAR/IMD domain-containing adapter protein 2

1

20

High-throughput

0.479

High

1396667

SRPRB
Signal recognition particle receptor subunit beta

1

20

High-throughput

0.479

High

1396669

FLVC1
Choline/ethanolamine transporter FLVCR1

1

10

High-throughput

0.479

High

1396670

S12A7
Solute carrier family 12 member 7

1

20

High-throughput

0.479

High

1396671

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

16

High-throughput

0.479

High

1396672

S4A7
Sodium bicarbonate cotransporter 3

1

18

High-throughput

0.479

High

1127754

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.458

High

128296

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

3

High-throughput

0.437

High

169133

ML12B
Myosin regulatory light chain 12B

1

9

High-throughput

0.437

High

215343

TXNL1
Thioredoxin-like protein 1

1

5

High-throughput

0.437

High

248615

FADS1
Acyl-CoA

1

14

High-throughput

0.437

High

333703

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

3

High-throughput

0.437

High

417683

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

10

High-throughput

0.437

High

573983

MYL6B
Myosin light chain 6B

1

14

High-throughput

0.437

High

673933

RS12
Small ribosomal subunit protein eS12

1

4

High-throughput

0.437

High

699019

CALX
Calnexin

1

9

High-throughput

0.437

High

776848

MYH11
Myosin-11

1

5

High-throughput

0.437

High

786218

LONM
Lon protease homolog, mitochondrial

1

16

High-throughput

0.437

High

867348

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.437

High

884199

SRP09
Signal recognition particle 9 kDa protein

1

8

High-throughput

0.437

High

912800

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

20

High-throughput

0.437

High

916191

BIEA
Biliverdin reductase A

1

5

High-throughput

0.437

High

916324

TXTP
Tricarboxylate transport protein, mitochondrial

1

13

High-throughput

0.437

High

938609

PSA
Puromycin-sensitive aminopeptidase

1

10

High-throughput

0.437

High

954580

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

9

High-throughput

0.437

High

973269

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

976765

ERF1
Eukaryotic peptide chain release factor subunit 1

1

6

High-throughput

0.437

High

991225

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

14

High-throughput

0.437

High

992057

RL38
Large ribosomal subunit protein eL38

1

3

High-throughput

0.437

High

1040358

DYST
Dystonin

1

20

High-throughput

0.437

High

1057231

PRDX1
Peroxiredoxin-1

1

7

High-throughput

0.437

High

1065364

SSRP1
FACT complex subunit SSRP1

1

9

High-throughput

0.437

High

1085914

TWF1
Twinfilin-1

1

3

High-throughput

0.437

High

1130390

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

11

High-throughput

0.437

High

1131355

GANAB
Neutral alpha-glucosidase AB

1

6

High-throughput

0.437

High

1143969

IPYR
Inorganic pyrophosphatase

1

8

High-throughput

0.437

High

1161046

FSCN1
Fascin

1

2

High-throughput

0.437

High

1271114

TM10C
tRNA methyltransferase 10 homolog C

1

7

High-throughput

0.437

High

1277769

MYH14
Myosin-14

1

5

High-throughput

0.437

High

1280040

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

High-throughput

0.437

High

1293035

RLGPB
Ral GTPase-activating protein subunit beta

1

19

High-throughput

0.437

High

1309479

CEP97
Centrosomal protein of 97 kDa

1

20

High-throughput

0.437

High

1353770

WIPF2
WAS/WASL-interacting protein family member 2

1

20

High-throughput

0.437

High

1365574

MY18A
Unconventional myosin-XVIIIa

1

18

High-throughput

0.437

High

1365882

NU205
Nuclear pore complex protein Nup205

1

5

High-throughput

0.437

High

1371503

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

13

High-throughput

0.437

High

1381059

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

1

High-throughput

0.437

High

1381328

NCLN
BOS complex subunit NCLN

1

9

High-throughput

0.437

High

1396105

Z512B
Zinc finger protein 512B

1

16

High-throughput

0.437

High

1396617

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.437

High

1396618

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

3

High-throughput

0.437

High

1396629

SFXN1
Sideroflexin-1

1

9

High-throughput

0.437

High

1396638

AAAS
Aladin

1

13

High-throughput

0.437

High

1396639

SYFB
Phenylalanine--tRNA ligase beta subunit

1

4

High-throughput

0.437

High

1396640

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

13

High-throughput

0.437

High

1396641

MDN1
Midasin

1

10

High-throughput

0.437

High

1396642

RM16
Large ribosomal subunit protein uL16m

1

7

High-throughput

0.437

High

1396644

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

7

High-throughput

0.437

High

1396651

DHCR7
7-dehydrocholesterol reductase

1

16

High-throughput

0.437

High

1396656

TMCO1
Calcium load-activated calcium channel

1

3

High-throughput

0.437

High

1396662

DDX52
Probable ATP-dependent RNA helicase DDX52

1

7

High-throughput

0.437

High

213231

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.249

Low

405528

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.249

Low

751338

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.249

Low

1099759

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025