HitPredict

Interactor 1: PIP12 (Q06611)
Aquaporin PIP1-2 (AtPIP1;2) (Plasma membrane intrinsic protein 1b) (PIP1b) (Transmembrane protein A) (AthH2) (TMP-A)
Gene: PIP1-2

Interactor 2: PIP26 (Q9ZV07)
Probable aquaporin PIP2-6 (Plasma membrane intrinsic protein 2-6) (AtPIP2;6) (Plasma membrane intrinsic protein 2e) (PIP2e)
Gene: PIP2-6

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	27609422, 21798944
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	MIP~MIP
Common GO terms	GO:0005886 - plasma membrane GO:0015250 - water channel activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 286 At			1 289
+	At
		988412 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP25_ARATH (1-285): 2.34e-104: 307: 78.60
+	At
		794925 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP22_ARATH (1-282): 4.04e-104: 306: 78.72
+	At
		1107211 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP25_ARATH (1-285): 2.34e-104: 307: 78.60
+	At
		794929 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP22_ARATH (1-282): 4.04e-104: 306: 78.72
+	At
		794711 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP21_ARATH (1-282): 2.24e-102: 302: 77.39
+	At
		673353 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP23_ARATH (1-282): 1.78e-101: 300: 77.31
+	At
		794727 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP21_ARATH (1-282): 2.24e-102: 302: 77.39
+	At
		955410 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP27_ARATH (1-284): 4.49e-101: 298: 75.70
+	At
		988286 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP24_ARATH (1-282): 1e-100: 298: 77.39
+	At
		673355 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP23_ARATH (1-282): 1.78e-101: 300: 77.31
+	At
		955415 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP27_ARATH (1-284): 4.49e-101: 298: 75.70
+	At
		988191 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP14_ARATH (3-278): 1.96e-97: 289: 68.12
+	At
		988442 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP28_ARATH (1-284): 1.75e-97: 289: 76.06
+	At
		1107212 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP28_ARATH (1-284): 1.75e-97: 289: 76.06
+	At
		988172 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP12_ARATH (2-278): 1.66e-95: 284: 67.15
+	At
		988174 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP13_ARATH (2-278): 9.82e-92: 275: 67.87
+	At
		902175 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP11_ARATH (2-278): 2.73e-91: 274: 66.79
+	At
		988230 PIP12_ARATH (1-286): 5.37e-117: 339: 100.00		PIP15_ARATH (3-277): 1.44e-91: 274: 68.36
+	At
		996284 PIP14_ARATH (1-286): 8.64e-116: 336: 93.73		PIP13_ARATH (2-278): 9.82e-92: 275: 67.87