HitPredict

Interactor 1: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	31180492, 19609304
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, molecular sieving, pull down, ion exchange chromatography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1312 Hs			1 1451
+	Hs
		724999 MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Hs
		1057382 SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Hs
		551826 DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Hs
		433185 LAMB1_HUMAN (457-960): 2.73e-09: 63.9: 18.88		FACD2_HUMAN (1-1441): 0: 2030: 100.00
+	Mm
		1143168 MYH10_MOUSE (52-818): 4.1e-25: 116: 8.56		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		971766 MYH6_MOUSE (524-1204): 1.28e-24: 114: 10.44		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1193842 MYH9_MOUSE (602-1198): 2.62e-23: 110: 8.58		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		528437 MYH3_MOUSE (56-776): 7.13e-22: 105: 9.22		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1194224 MY18A_MOUSE (158-674): 7.22e-20: 98.8: 14.26		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1194025 SMC1A_MOUSE (290-1274): 4e-19: 96.1: 11.16		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		93874 E9QPE7_MOUSE (60-652): 7.89e-16: 85.6: 8.86		FACD2_MOUSE (1-1439): 0: 1973: 74.76
+	Mm
		1132060 MYH1_MOUSE (785-1234): 1.57e-15: 84.4: 12.50		FACD2_MOUSE (1-1439): 0: 1973: 74.76