Protein: TBL1R
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)

Gene: TBL1R, TBL1XR1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q9BZK7

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0001835 - blastocyst hatching
GO:0002021 - response to dietary excess

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245633

TBL1X
F-box-like/WD repeat-containing protein TBL1X

4

16

Small-scale

0.890

High

1309163

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

18

High-throughput

0.811

High

1318177

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

2

12

Small-scale

0.754

High

261584

NCOR1
Nuclear receptor corepressor 1

9

20

Small-scale

0.751

High

177377

HDAC3
Histone deacetylase 3

7

16

Small-scale

0.746

High

1082374

DDB1
DNA damage-binding protein 1

1

12

Small-scale

0.724

High

487742

ANDR
Androgen receptor

5

20

Small-scale

0.702

High

1028204

GPS2
G protein pathway suppressor 2

4

2

High-throughput

0.699

High

848120

MECP2
Methyl-CpG-binding protein 2

4

5

Small-scale

0.699

High

370377

ESR1
Estrogen receptor

4

20

Small-scale

0.672

High

880817

HDAC4
Histone deacetylase 4

3

20

High-throughput

0.656

High

930379

UBC9
SUMO-conjugating enzyme UBC9

1

7

Small-scale

0.647

High

1222735

MKX
Homeobox protein Mohawk

2

4

High-throughput

0.628

High

734486

ARL2
ADP-ribosylation factor-like protein 2

2

7

High-throughput

0.628

High

868724

ATX1
Ataxin-1

2

3

High-throughput

0.628

High

964245

FOXK2
Forkhead box protein K2

2

11

Small-scale

0.619

High

1162302

WDR59
GATOR2 complex protein WDR59

1

18

High-throughput

0.618

High

849435

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

5

Small-scale

0.618

High

1282344

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

5

Small-scale

0.618

High

1318178

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.618

High

1318188

HDAC5
Histone deacetylase 5

2

20

High-throughput

0.611

High

1318191

T22D4
TSC22 domain family protein 4

2

3

High-throughput

0.611

High

259975

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

3

8

High-throughput

0.609

High

1152384

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

917881

H4
Histone H4

2

7

Small-scale

0.595

High

228612

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

717329

CTNB1
Catenin beta-1

2

10

Small-scale

0.584

High

1039829

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.575

High

1153371

PKHA7
Pleckstrin homology domain-containing family A member 7

1

19

High-throughput

0.575

High

1171594

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

146860

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

2

High-throughput

0.536

High

208062

HAIR
Lysine-specific demethylase hairless

1

2

High-throughput

0.536

High

232484

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.536

High

804333

NOTC1
Neurogenic locus notch homolog protein 1

1

8

High-throughput

0.536

High

840414

ERF
ETS domain-containing transcription factor ERF

1

15

High-throughput

0.536

High

952865

FOXK1
Forkhead box protein K1

1

11

High-throughput

0.536

High

996881

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1038686

HDAC1
Histone deacetylase 1

1

19

High-throughput

0.536

High

1050769

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

1126952

EFMT2
EEF1A lysine methyltransferase 2

1

1

High-throughput

0.536

High

1199094

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

3

High-throughput

0.536

High

1234135

ZN276
Zinc finger protein 276

1

2

High-throughput

0.536

High

1260185

HDAC7
Histone deacetylase 7

1

20

High-throughput

0.536

High

521300

SKI
Ski oncogene

1

0

Small-scale

0.530

High

831669

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.527

High

1238849

TTC29
Tetratricopeptide repeat protein 29

1

0

High-throughput

0.517

High

839109

EMD
Emerin

1

2

Small-scale

0.515

High

158029

KLF11
Krueppel-like factor 11

1

13

High-throughput

0.515

High

175177

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

14

High-throughput

0.501

High

1087388

H2B2E
Histone H2B type 2-E

1

6

Small-scale

0.501

High

336596

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

151893

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.489

High

324014

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

611334

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.489

High

813730

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.489

High

829623

DGKG
Diacylglycerol kinase gamma

1

2

High-throughput

0.489

High

847950

CP2J2
Cytochrome P450 2J2

1

1

High-throughput

0.489

High

1167084

KSR2
Kinase suppressor of Ras 2

1

6

High-throughput

0.489

High

1290935

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.489

High

1302163

TCPQM
T-complex protein 1 subunit theta-like 2

1

20

High-throughput

0.489

High

1318182

HAOX2
2-Hydroxyacid oxidase 2

1

1

High-throughput

0.489

High

1318189

CCL26
C-C motif chemokine 26

1

1

High-throughput

0.489

High

1318192

CCDC9
Coiled-coil domain-containing protein 9

1

1

High-throughput

0.489

High

126168

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

9

Small-scale

0.479

High

135156

NFIB
Nuclear factor 1 B-type

1

8

High-throughput

0.479

High

163237

XPO1
Exportin-1

1

13

High-throughput

0.479

High

167390

SMAD7
Mothers against decapentaplegic homolog 7

1

4

Small-scale

0.479

High

211960

TLX3
T-cell leukemia homeobox protein 3

1

10

High-throughput

0.479

High

244901

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.479

High

443244

NFIC
Nuclear factor 1 C-type

1

15

High-throughput

0.479

High

488022

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.479

High

500446

THA
Thyroid hormone receptor alpha

1

20

Small-scale

0.479

High

500505

THB
Thyroid hormone receptor beta

1

20

Small-scale

0.479

High

570041

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

595684

BCL3
B-cell lymphoma 3 protein

1

9

Small-scale

0.479

High

620419

GATA2
Endothelial transcription factor GATA-2

1

10

High-throughput

0.479

High

620569

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

10

High-throughput

0.479

High

637999

PSA3
Proteasome subunit alpha type-3

1

5

Small-scale

0.479

High

672284

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

9

High-throughput

0.479

High

740596

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.479

High

749840

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

799000

GATA4
Transcription factor GATA-4

1

10

High-throughput

0.479

High

799147

NKX21
Homeobox protein Nkx-2.1

1

11

High-throughput

0.479

High

801949

RECQ1
ATP-dependent DNA helicase Q1

1

18

High-throughput

0.479

High

818441

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

921419

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

Small-scale

0.479

High

935208

H31
Histone H3.1

1

11

High-throughput

0.479

High

974674

MECOM
Histone-lysine N-methyltransferase MECOM

1

4

High-throughput

0.479

High

995204

GOGA2
Golgin subfamily A member 2

1

9

High-throughput

0.479

High

1021159

FOXC1
Forkhead box protein C1

1

12

High-throughput

0.479

High

1029841

TIF1B
Transcription intermediary factor 1-beta

1

13

High-throughput

0.479

High

1033727

IKZF1
DNA-binding protein Ikaros

1

6

High-throughput

0.479

High

1036051

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

Small-scale

0.479

High

1043562

CUL4B
Cullin-4B

1

20

Small-scale

0.479

High

1148776

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1188826

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1236482

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

Small-scale

0.479

High

1254912

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

1269548

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1270423

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.479

High

1304089

RING2
E3 ubiquitin-protein ligase RING2

1

16

High-throughput

0.479

High

1318179

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1318180

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1318181

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

8

Small-scale

0.479

High

1318183

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

1318185

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1318186

IKZF3
Zinc finger protein Aiolos

1

7

High-throughput

0.479

High

1318187

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

262570

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

781447

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.445

High

1044128

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.445

High

1302326

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.445

High

1303718

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.445

High

344128

ANT3
Antithrombin-III

1

4

High-throughput

0.437

High

385480

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

1302754

RUFY1
RUN and FYVE domain-containing protein 1

1

11

High-throughput

0.437

High

1318190

NINL
Ninein-like protein

1

13

High-throughput

0.437

High

1154424

LIN54
Protein lin-54 homolog

1

0

Small-scale

0.426

High

1318184

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

5

High-throughput

0.407

High

1070092

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

0

High-throughput

0.347

High

151347

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024