HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	18850735
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 1121
+	Hs
		929601 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		1272691 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		1256655 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		GEMI5_HUMAN (758-1120): 9.39e-16: 85.1: 9.37
+	Hs
		903414 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	At
		1227309 CSN5A_ARATH (1-334): 5.43e-121: 354: 65.69		GPLPC_ARATH (37-239): 6.59e-11: 66.8: 10.43
+	Hs
		176993 EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		124824 EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		130829 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		124920 EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		124819 EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Sc
		984246 RPN8_YEAST (53-326): 4.45e-57: 190: 16.61		CIAO1_YEAST (110-382): 1.5e-14: 78.3: 18.02
+	Hs
		1138819 MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58