HitPredict

Interactor 1: DYLT (Q94524)
Dynein light chain Tctex-type (TCTEX-1 protein homolog)
Gene: Dlc90F

Interactor 2: Q9VH45 (Q9VH45)
Dynein light chain (RE37471p)
Gene: DmelCG5359

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	14605208, 37061542, unassigned2874
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Tctex-1~Tctex-1
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex GO:0007018 - microtubule-based movement GO:0030286 - dynein complex GO:0045505 - dynein intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 111 Dm			1 173
+	Hs
		928647 DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30		DYT2B_HUMAN (31-173): 1.89e-53: 168: 32.64
+	Hs
		850536 DYLT3_HUMAN (6-111): 2.38e-43: 138: 48.11		DYT2B_HUMAN (31-173): 1.89e-53: 168: 32.64
+	Dm
		1178518 DYLT_DROME (1-111): 5.26e-45: 143: 100.00		Q7K035_DROME (18-172): 2.66e-49: 159: 19.75
+	Hs
		850527 DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30		DYLT3_HUMAN (62-170): 2.11e-46: 149: 21.10
+	Cr
		249526 O64980_CHLRE (1-111): 3.16e-46: 146: 55.86		O64980_CHLRE (61-170): 3.22e-45: 146: 27.93
+	Hs
		928580 DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30		DYLT1_HUMAN (64-170): 1.83e-45: 146: 22.43
+	Hs
		850524 DYLT3_HUMAN (6-111): 2.38e-43: 138: 48.11		DYLT3_HUMAN (62-170): 2.11e-46: 149: 21.10
+	Dm
		1276651 DYLT_DROME (1-111): 5.26e-45: 143: 100.00		DYLT_DROME (62-170): 3.78e-44: 143: 22.94
+	Hs
		928610 DYLT1_HUMAN (4-111): 1.09e-45: 144: 71.30		DYLT4_HUMAN (33-171): 3.79e-41: 139: 30.94
+	Hs
		1127236 DYT2B_HUMAN (1-108): 8.69e-37: 123: 23.85		DYLT4_HUMAN (33-171): 3.79e-41: 139: 30.94