HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 783
+	Hs
		1344140 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		128255 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		127936 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		128019 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		134229 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571615 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		1283854 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1344198 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		516711 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		134054 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		134157 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571464 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		181700 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		DDX3Y_HUMAN (5-581): 7.35e-132: 408: 23.48
+	Hs
		134268 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		134166 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		134018 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		133858 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		516391 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23