HitPredict

Interactor 1: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 680 Hs			1 2997
+	Hs
		229523 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Mm
		101401 F8VPM0_MOUSE (4-648): 1.11e-55: 208: 12.69		SMCA5_MOUSE (847-1893): 0: 928: 27.25
+	Mm
		1265217 BAZ2A_MOUSE (4-648): 1.17e-55: 208: 12.69		SMCA5_MOUSE (847-1893): 0: 928: 27.25
+	Hs
		229519 BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		1059944 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		229518 BAZ2B_HUMAN (2-648): 3.37e-43: 170: 12.25		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		229399 CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		658750 BAZ2B_HUMAN (2-648): 3.37e-43: 170: 12.25		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		658672 CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		847115 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		1018732 KDM5B_HUMAN (147-656): 5.55e-61: 224: 13.90		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Dm
		1097639 Q9VID9_DROME (50-537): 4.07e-42: 167: 15.32		ISWI_DROME (850-1894): 0: 884: 26.45
+	Hs
		1254436 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		CHD6_HUMAN (2109-2989): 0: 691: 29.39
+	Dm
		332869 KDM5_DROME (79-655): 3.77e-57: 212: 11.99		CHDM_DROME (506-1897): 0: 830: 24.74
+	Dm
		332724 CHDM_DROME (173-626): 2.63e-48: 185: 16.10		CHDM_DROME (506-1897): 0: 830: 24.74
+	Hs
		1059928 BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		782323 KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		1018602 CHD5_HUMAN (255-617): 2.01e-43: 170: 16.79		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		1059751 CHD5_HUMAN (255-617): 2.01e-43: 170: 16.79		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		1285361 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		CHD8_HUMAN (1-976): 4.16e-09: 65.1: 7.67