Protein: DDX18
Probable ATP-dependent RNA helicase pitchoune (EC 3.6.4.13)

Gene: DDX18, pit
Organism: Drosophila melanogaster
Interactions: 114
UniProt ID: Q9VD51

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1261340

Q7JQN4
RNA helicase

2

16

High-throughput

0.737

High

1264470

BOP1
Ribosome biogenesis protein BOP1 homolog

2

20

High-throughput

0.737

High

1266314

Q7K4B2
LD47540p

2

20

High-throughput

0.737

High

1344123

Q8SY39
ATP-dependent RNA helicase DDX54

2

19

High-throughput

0.737

High

1471245

DDX47
ATP-dependent RNA helicase DDX47

2

17

High-throughput

0.737

High

356840

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

20

High-throughput

0.575

High

1060664

DDX49
Probable ATP-dependent RNA helicase Dbp45A

1

19

High-throughput

0.575

High

1173943

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

20

High-throughput

0.575

High

1237372

Q6NQY9
ATP-dependent RNA helicase

1

17

High-throughput

0.575

High

1266515

Q7K4L8
RNA helicase

1

12

High-throughput

0.575

High

1285360

Y8611
Probable ATP-dependent RNA helicase CG8611

1

18

High-throughput

0.575

High

1467051

Q9V9U9
Nucleolar protein 16

1

1

High-throughput

0.575

High

1471256

Q9VRI0
Probable ATP-dependent RNA helicase DDX56

1

17

High-throughput

0.575

High

1471267

RENT1
Regulator of nonsense transcripts 1 homolog

1

13

High-throughput

0.575

High

54891

A1Z909
LD11307p

2

12

High-throughput

0.571

High

1263228

Q7JXU4
Nucleolar GTP-binding protein 2

2

19

High-throughput

0.571

High

1378633

Q95WY3
Nucleolar protein 56

2

16

High-throughput

0.571

High

1464931

NOG1
Nucleolar GTP-binding protein 1

2

12

High-throughput

0.571

High

1470868

Q9VCY1
RRM domain-containing protein

2

20

High-throughput

0.571

High

1471244

NOC3L
Nucleolar complex protein 3

2

16

High-throughput

0.571

High

1471248

Q9VKC1
IP16805p

2

17

High-throughput

0.571

High

1471253

Q9VM69
Nucleolar protein 58

2

16

High-throughput

0.571

High

1471263

Q9VXK5
Putative rRNA methyltransferase

2

12

High-throughput

0.571

High

1471266

RRP12
RRP12-like protein

2

3

High-throughput

0.571

High

1471270

Q9VZF5
Kinesin-like protein

2

13

High-throughput

0.571

High

1471276

Q9W3B2
Protein MAK16 homolog

2

5

High-throughput

0.571

High

1471277

NAT10
RNA cytidine acetyltransferase

2

6

High-throughput

0.571

High

1471235

Q9VDK7
Signal recognition particle subunit SRP72

2

4

High-throughput

0.521

High

1471238

Q9VEP0
Regulatory protein zeste

2

3

High-throughput

0.521

High

1471255

Q9VQI5
Interferon-related developmental regulator 1

2

1

High-throughput

0.521

High

1471252

Y3096
Ribosomal L1 domain-containing protein CG13096

1

13

High-throughput

0.514

High

1440300

Q9I7K8
FI07222p

1

9

High-throughput

0.489

High

929405

FKB39
39 kDa FK506-binding nuclear protein

1

9

Small-scale

0.479

High

1321624

GNL3
Guanine nucleotide-binding protein-like 3 homolog

1

19

High-throughput

0.479

High

1471274

Q9W0R0
Cell division cycle 5, isoform A

1

8

High-throughput

0.479

High

1471259

FRL
Formin-like protein

1

1

High-throughput

0.457

High

55810

A1Z9K0
Uncharacterized protein, isoform B

1

13

High-throughput

0.445

High

58103

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.445

High

120672

M9PE01
cyclin-dependent kinase

1

7

High-throughput

0.445

High

263400

PENG
Protein penguin

1

7

High-throughput

0.445

High

704384

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.445

High

852961

ACTZ
Actin-related protein 1

1

5

High-throughput

0.445

High

875271

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.445

High

909874

PFKA
ATP-dependent 6-phosphofructokinase

1

1

High-throughput

0.445

High

911765

POLO
Serine/threonine-protein kinase polo

1

5

High-throughput

0.445

High

1176011

MCM4
DNA replication licensing factor MCM4

1

10

High-throughput

0.445

High

1265148

RRP8
Ribosomal RNA-processing protein 8

1

6

High-throughput

0.445

High

1302230

Q8I937
Ribosome biogenesis regulatory protein

1

6

High-throughput

0.445

High

1321447

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1346056

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

3

High-throughput

0.445

High

1378476

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.445

High

1464434

Q9V3V6
26S proteasome regulatory complex subunit p50

1

11

High-throughput

0.445

High

1464855

Q9V405
26S proteasome regulatory subunit 6B

1

6

High-throughput

0.445

High

1465121

API5
Apoptosis inhibitor 5 homolog

1

3

High-throughput

0.445

High

1465172

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1467186

EBP2
Probable rRNA-processing protein EBP2 homolog

1

6

High-throughput

0.445

High

1467948

Q9VAH7
N-terminal kinase-like protein

1

5

High-throughput

0.445

High

1468521

LARP
La-related protein 1

1

14

High-throughput

0.445

High

1471234

PPAN
Protein Peter pan

1

9

High-throughput

0.445

High

1471236

SURF6
Surfeit locus protein 6 homolog

1

7

High-throughput

0.445

High

1471239

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

10

High-throughput

0.445

High

1471240

Q9VG84
DNA ligase

1

1

High-throughput

0.445

High

1471241

RLP24
Probable ribosome biogenesis protein RLP24

1

9

High-throughput

0.445

High

1471247

RPF1
Probable ribosome production factor 1

1

13

High-throughput

0.445

High

1471251

PESC
Pescadillo homolog

1

8

High-throughput

0.445

High

1471257

SRP68
Signal recognition particle subunit SRP68

1

7

High-throughput

0.445

High

1471258

Q9VTF8
Mitochondrial ribosomal protein L2

1

10

High-throughput

0.445

High

1471264

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1471265

Q9VXR5
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.445

High

1471268

Q9VZ88
AT07585p

1

20

High-throughput

0.445

High

1471269

BRX1
Ribosome biogenesis protein BRX1 homolog

1

18

High-throughput

0.445

High

1471275

Q9W0T7
Dis3 like 3'-5' exoribonuclease 2, isoform A

1

9

High-throughput

0.445

High

1471278

NOP53
Ribosome biogenesis protein NOP53

1

9

High-throughput

0.445

High

1471279

Q9W414
Regulatory particle triple-A ATPase 4

1

6

High-throughput

0.445

High

1471281

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.445

High

1175144

NETB
Netrin-B

1

4

High-throughput

0.442

High

120352

M9PD17
Gigas, isoform B

1

2

High-throughput

0.437

High

1377380

Q95RF6
LD34461p

1

2

High-throughput

0.437

High

1378551

FOXO
Forkhead box protein O

1

6

High-throughput

0.437

High

2501

NOVA
RNA-binding protein Pasilla

1

20

High-throughput

0.407

High

53157

A1Z7K8
AaRS-interacting multifunctional protein 1

1

2

High-throughput

0.407

High

55465

A1Z9E3
Elongation factor Tu

1

1

High-throughput

0.407

High

95244

E1JIH4
Uncharacterized protein, isoform D

1

2

High-throughput

0.407

High

119073

M9NFI9
Neurabin-1

1

7

High-throughput

0.407

High

304530

AUB
Protein aubergine

1

7

High-throughput

0.407

High

360567

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.407

High

782768

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

4

High-throughput

0.407

High

852216

COPB
Coatomer subunit beta

1

2

High-throughput

0.407

High

1059169

ROP
Protein ROP

1

3

High-throughput

0.407

High

1069760

Q0E931
GTP-binding protein 1

1

5

High-throughput

0.407

High

1234114

SARM1
NAD(+) hydrolase sarm1

1

9

High-throughput

0.407

High

1268351

DYM
Dymeclin

1

1

High-throughput

0.407

High

1285812

Q86BS3
Chromator, isoform A

1

2

High-throughput

0.407

High

1304786

Q8IPU8
BNIP3, isoform B

1

1

High-throughput

0.407

High

1344237

Q8SY53
GH11935p

1

4

High-throughput

0.407

High

1465446

Q9V455
Importin subunit alpha

1

6

High-throughput

0.407

High

1466744

Q9V9Q4
LD43819p

1

3

High-throughput

0.407

High

1468467

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

3

High-throughput

0.407

High

1468592

Q9VAX8
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.407

High

1471237

Q9VEH0
Aluminum tubes, isoform A

1

14

High-throughput

0.407

High

1471242

IPO9
Importin-9

1

15

High-throughput

0.407

High

1471243

Q9VI53
LD44267p

1

9

High-throughput

0.407

High

1471246

RRP1L
Ribosomal RNA processing protein 1 homolog

1

12

High-throughput

0.407

High

1471249

NFS1
Cysteine desulfurase, mitochondrial

1

1

High-throughput

0.407

High

1471250

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

13

High-throughput

0.407

High

1471260

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

4

High-throughput

0.407

High

1471261

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

3

High-throughput

0.407

High

1471262

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

4

High-throughput

0.407

High

1471271

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.407

High

1471272

Q9W0E4
Aminopeptidase

1

3

High-throughput

0.407

High

1471273

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.407

High

1471280

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

1

High-throughput

0.407

High

1471254

Q9VM98
AT06841p1

1

0

High-throughput

0.265

Low

1172040

DALY
Division abnormally delayed protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025