Interactor 1: OPTN (Q96CV9)
Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
Gene: OPTN

Interactor 2: TBC17 (Q9HA65)
TBC1 domain family member 17
Gene: TBC1D17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.688

The method score is based on:

Property Details
Experiments 16189514, 31723608, 22854040
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0006914 - autophagy
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 577
Hs

1 648
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024