Protein: WDR20
WD repeat-containing protein 20 (Protein DMR)

Gene: WDR20
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q8TBZ3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0035800 - deubiquitinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

967160

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

12

16

Small-scale

0.978

High

1347129

WDR48
WD repeat-containing protein 48

10

19

Small-scale

0.977

High

275906

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

12

16

Small-scale

0.976

High

247388

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

5

10

Small-scale

0.930

High

1349262

FERM2
Fermitin family homolog 2

3

1

High-throughput

0.855

High

1349261

FBXW5
F-box/WD repeat-containing protein 5

4

0

High-throughput

0.853

High

1349277

DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

2

12

High-throughput

0.732

High

1256830

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

4

5

Small-scale

0.699

High

1349264

OPTN
Optineurin

4

20

High-throughput

0.697

High

1349266

ALS2
Alsin

1

7

High-throughput

0.691

High

946022

VSX2
Visual system homeobox 2

3

10

High-throughput

0.667

High

1049590

1433F
14-3-3 protein eta

3

20

High-throughput

0.662

High

1330814

TSYL6
Testis-specific Y-encoded-like protein 6

3

4

High-throughput

0.662

High

375753

RASK
GTPase KRas

3

7

High-throughput

0.640

High

1349273

VSX1
Visual system homeobox 1

3

9

High-throughput

0.640

High

1252070

RN19B
E3 ubiquitin-protein ligase RNF19B

2

14

High-throughput

0.628

High

1349274

HSPB8
Heat shock protein beta-8

2

6

High-throughput

0.628

High

1349278

TRI35
E3 ubiquitin-protein ligase TRIM35

2

6

High-throughput

0.628

High

317199

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

20

High-throughput

0.618

High

1254753

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.618

High

1326495

ARL14
ADP-ribosylation factor-like protein 14

1

4

High-throughput

0.618

High

1349269

DDX31
ATP-dependent DNA helicase DDX31

1

11

High-throughput

0.618

High

966651

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

1204377

SGO1
Shugoshin 1

2

0

High-throughput

0.576

High

342973

HERC2
E3 ubiquitin-protein ligase HERC2

1

10

High-throughput

0.575

High

1178956

TM266
Transmembrane protein 266

2

1

High-throughput

0.574

High

396568

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

710382

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.553

High

845732

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.553

High

1187506

AR13B
ADP-ribosylation factor-like protein 13B

1

9

High-throughput

0.553

High

1349272

ARL15
ADP-ribosylation factor-like protein 15

1

9

High-throughput

0.553

High

180346

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

2

High-throughput

0.536

High

354739

PAK4
Serine/threonine-protein kinase PAK 4

1

5

High-throughput

0.536

High

461738

HS90A
Heat shock protein HSP 90-alpha

1

8

High-throughput

0.536

High

543243

UBL4A
Ubiquitin-like protein 4A

1

9

High-throughput

0.536

High

714637

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

16

High-throughput

0.536

High

730077

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

971807

1433E
14-3-3 protein epsilon

1

4

High-throughput

0.536

High

973989

RUXF
Small nuclear ribonucleoprotein F

1

12

High-throughput

0.536

High

990527

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1157540

PKN2
Serine/threonine-protein kinase N2

1

13

High-throughput

0.536

High

1349270

I17RB
Interleukin-17 receptor B

1

2

High-throughput

0.536

High

1349279

USH1C
Harmonin

1

7

High-throughput

0.536

High

156057

SOCS6
Suppressor of cytokine signaling 6

1

12

High-throughput

0.515

High

596252

H12
Histone H1.2

1

9

High-throughput

0.515

High

442414

GELS
Gelsolin

1

3

High-throughput

0.515

High

471148

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

1046392

UBXN1
UBX domain-containing protein 1

1

0

High-throughput

0.513

High

1149670

SURF2
Surfeit locus protein 2

1

0

High-throughput

0.513

High

1349263

R51A1
RAD51-associated protein 1

1

0

High-throughput

0.513

High

1349271

RPRM
Protein reprimo

1

0

High-throughput

0.513

High

1091543

DLG1
Disks large homolog 1

1

1

High-throughput

0.501

High

1307586

ZDH17
Palmitoyltransferase ZDHHC17

1

8

High-throughput

0.494

High

252945

UD19
UDP-glucuronosyltransferase 1A9

1

1

High-throughput

0.489

High

270576

LRP4
Low-density lipoprotein receptor-related protein 4

1

1

High-throughput

0.489

High

1349276

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.489

High

892703

DNLI4
DNA ligase 4

1

1

High-throughput

0.481

High

173112

XPO1
Exportin-1

1

16

High-throughput

0.479

High

218518

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

260202

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

463666

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

520216

ANDR
Androgen receptor

1

20

Small-scale

0.479

High

540579

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

674258

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

691267

1433T
14-3-3 protein theta

1

20

Small-scale

0.479

High

715684

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

934890

TERA
Transitional endoplasmic reticulum ATPase

1

6

Small-scale

0.479

High

956415

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

1119973

CIRBP
Cold-inducible RNA-binding protein

1

10

High-throughput

0.479

High

1287385

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

6

Small-scale

0.479

High

1349260

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

650313

FGFR3
Fibroblast growth factor receptor 3

1

11

High-throughput

0.470

High

407196

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

Small-scale

0.458

High

259003

DNJA2
DnaJ homolog subfamily A member 2

1

12

High-throughput

0.445

High

1349265

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

1

5

High-throughput

0.445

High

1349268

HIRP3
HIRA-interacting protein 3

1

1

High-throughput

0.445

High

287595

LRP6
Low-density lipoprotein receptor-related protein 6

1

1

Small-scale

0.437

High

374085

RASN
GTPase NRas

1

8

High-throughput

0.437

High

562257

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.437

High

1349275

AMFR
E3 ubiquitin-protein ligase AMFR

1

9

Small-scale

0.437

High

1349267

THUM3
tRNA

1

0

High-throughput

0.426

High

1234462

MRM1
rRNA methyltransferase 1, mitochondrial

3

0

High-throughput

0.347

High

569042

COBA2

1

0

High-throughput

0.279

Low

1007884

X3CL1
Fractalkine

1

0

High-throughput

0.279

Low

1233373

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1276235

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1293084

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025