Interactor 1: I17RA (Q96F46)
Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CDw217) (CD antigen CD217)
Gene: IL17RA

Interactor 2: IL17F (Q96PD4)
Interleukin-17F (IL-17F) (Cytokine ML-1)
Gene: IL17F

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 18684971, 19838198
Identification Methods solid phase assay, surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL17~IL17R_fnIII_D1, IL17~IL17R_fnIII_D2
Common GO terms GO:0005576 - extracellular region
GO:0006954 - inflammatory response
GO:0032755 - positive regulation of interleukin-6 production
GO:0045087 - innate immune response
GO:0097400 - interleukin-17-mediated signaling pathway
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 866
Hs

1 163
+ Hs
+ Mm
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024