HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 728 Hs			1 444
+	Hs
		129330 P85B_HUMAN (1-728): 0: 549: 100.00		TBB6_HUMAN (1-432): 0: 703: 92.13
+	Dm
		337680 SRC64_DROME (550-722): 2.59e-33: 137: 18.23		TBB1_DROME (1-429): 0: 705: 96.50
+	Hs
		411549 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		933767 BTK_HUMAN (551-727): 5.38e-31: 131: 20.65		TBB4B_HUMAN (1-427): 0: 707: 98.36
+	Hs
		411668 LCK_HUMAN (519-724): 4.43e-31: 130: 21.40		TBB4B_HUMAN (1-427): 0: 707: 98.36
+	Hs
		427991 SRC_HUMAN (535-728): 1.04e-28: 123: 18.81		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		428098 BLK_HUMAN (556-724): 7.19e-29: 123: 22.16		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		381102 LYN_HUMAN (527-724): 1.21e-29: 125: 18.78		TBB4A_HUMAN (1-427): 0: 702: 97.42
+	Hs
		548704 VAV_HUMAN (621-719): 3.02e-14: 78.7: 34.00		TBB3_HUMAN (1-444): 0: 712: 92.57
+	Hs
		428001 VAV_HUMAN (621-719): 3.02e-14: 78.7: 34.00		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		924548 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		TBB3_HUMAN (1-444): 0: 712: 92.57
+	Hs
		548681 VAV_HUMAN (621-719): 3.02e-14: 78.7: 34.00		TBB4B_HUMAN (1-427): 0: 707: 98.36
+	Hs
		428131 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		924460 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		TBB4B_HUMAN (1-427): 0: 707: 98.36
+	Hs
		381112 VAV_HUMAN (621-719): 3.02e-14: 78.7: 34.00		TBB4A_HUMAN (1-427): 0: 702: 97.42
+	Hs
		924836 GRB2_HUMAN (329-411): 1.45e-14: 75.2: 31.40		TBB6_HUMAN (1-432): 0: 703: 92.13