HitPredict

Interactor 1: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1378 Hs			1 372
+	Hs
		260971 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		555597 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		1087083 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24
+	Hs
		1151369 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02
+	Hs
		1293188 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2AJ_HUMAN (1-126): 1.06e-63: 201: 60.47
+	Hs
		391842 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470504 TONSL_HUMAN (1-1378): 0: 641: 100.00		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		260693 TNKS1_HUMAN (328-846): 2.79e-46: 184: 12.75		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		260986 BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		1296210 TANC1_HUMAN (73-1074): 3.83e-65: 246: 11.04		H2A1H_HUMAN (1-125): 5.02e-64: 201: 60.94
+	Hs
		555617 BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		1087090 BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18		H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24
+	Hs
		391861 BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		555536 ANKH1_HUMAN (299-583): 1.68e-18: 94.7: 17.24		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		391781 ANKH1_HUMAN (299-583): 1.68e-18: 94.7: 17.24		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470446 ANKH1_HUMAN (299-583): 1.68e-18: 94.7: 17.24		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		1237344 ANR31_HUMAN (503-636): 7.71e-13: 75.9: 36.69		H2A1H_HUMAN (1-125): 5.02e-64: 201: 60.94