HitPredict

Interactor 1: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 314 Hs			1 1620
+	Hs
		434262 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		RET_HUMAN (842-1477): 4.8e-137: 455: 23.56
+	Hs
		445868 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		ROS1_HUMAN (1039-1461): 3.68e-112: 397: 37.75
+	Hs
		508150 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411470 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435731 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		1081567 DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03