HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TRAIP (Q9BWF2)
E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (TRAF-interacting protein)
Gene: TRAIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17544371
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 469
+	Hs
		1024752 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TRAIP_HUMAN (1-469): 1.32e-114: 346: 100.00
+	Hs
		1020906 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		TRAIP_HUMAN (1-469): 1.32e-114: 346: 100.00
+	Mm
		761832 TRAF2_MOUSE (28-554): 5.26e-102: 318: 33.46		TRAIP_MOUSE (1-467): 1.17e-109: 334: 79.70
+	Hs
		1314608 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		TRAIP_HUMAN (1-469): 1.32e-114: 346: 100.00
+	Mm
		936267 TRAF6_MOUSE (21-551): 2.76e-83: 271: 22.20		TRAIP_MOUSE (1-467): 1.17e-109: 334: 79.70
+	Hs
		1023787 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		TRAIP_HUMAN (1-469): 1.32e-114: 346: 100.00
+	Mm
		1141401 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		EP15R_MOUSE (12-185): 1.5e-09: 62.6: 8.62
+	Hs
		787905 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		EPS15_HUMAN (3-170): 2.69e-10: 64.9: 14.53
+	Hs
		728474 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		MYH11_HUMAN (29-307): 1.74e-09: 62.5: 17.07
+	Dm
		1179373 Q960H6_DROME (124-550): 9.53e-66: 222: 20.05		Q7K2X1_DROME (7-294): 2.71e-30: 123: 23.65
+	Dm
		1179391 Q9VXG5_DROME (153-550): 5.24e-61: 208: 19.28		Q7K2X1_DROME (7-294): 2.71e-30: 123: 23.65
+	Hs
		725088 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		MYH9_HUMAN (41-307): 2.24e-09: 62.1: 14.47
+	Hs
		724993 TRAF4_HUMAN (29-551): 2.98e-73: 243: 23.32		MYH9_HUMAN (41-307): 2.24e-09: 62.1: 14.47
+	Hs
		1357714 TRI35_HUMAN (25-469): 6.8e-57: 200: 11.82		MRCKB_HUMAN (26-379): 7.39e-16: 82.6: 13.02
+	Hs
		1189797 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		MYH14_HUMAN (75-300): 3.34e-19: 93.3: 15.66
+	Hs
		1052780 TRI25_HUMAN (38-387): 1.04e-43: 166: 15.43		MYO5C_HUMAN (11-401): 4.42e-11: 67.6: 10.35
+	Hs
		1012561 TRAF7_HUMAN (17-297): 2.01e-44: 168: 20.81		CGNL1_HUMAN (65-280): 2.19e-10: 65.2: 10.66
+	Hs
		725238 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		MYH10_HUMAN (77-300): 1.02e-09: 63.3: 14.40
+	Hs
		725005 TRI31_HUMAN (34-365): 4.69e-41: 155: 16.42		MYH9_HUMAN (41-307): 2.24e-09: 62.1: 14.47
+	Hs
		724926 LNX1_HUMAN (33-165): 1.33e-12: 72.6: 21.81		MYH9_HUMAN (41-307): 2.24e-09: 62.1: 14.47