HitPredict

Interactor 1: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Interactor 2: NKX31 (Q99801)
Homeobox protein Nkx-3.1 (Homeobox protein NK-3 homolog A)
Gene: NKX3-1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27339988
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071466 - cellular response to xenobiotic stimulus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 234
+	Hs
		679157 EHMT2_HUMAN (21-1210): 0: 909: 100.00		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		1296426 EHMT2_HUMAN (21-1210): 0: 909: 100.00		VSX1_HUMAN (3-196): 1.22e-30: 118: 18.97
+	Hs
		211935 EHMT2_HUMAN (21-1210): 0: 909: 100.00		TLX3_HUMAN (112-215): 4.85e-31: 117: 40.00
+	Hs
		213370 EHMT2_HUMAN (21-1210): 0: 909: 100.00		TLX2_HUMAN (114-196): 1.57e-12: 67: 48.19
+	Hs
		1306495 EHMT1_HUMAN (1-1209): 0: 685: 45.63		NKX31_HUMAN (1-234): 2.21e-45: 153: 100.00
+	Hs
		679173 EHMT1_HUMAN (1-1209): 0: 685: 45.63		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		1334136 EHMT1_HUMAN (1-1209): 0: 685: 45.63		VSX1_HUMAN (3-196): 1.22e-30: 118: 18.97
+	Hs
		211969 EHMT1_HUMAN (1-1209): 0: 685: 45.63		TLX3_HUMAN (112-215): 4.85e-31: 117: 40.00
+	Hs
		213385 EHMT1_HUMAN (1-1209): 0: 685: 45.63		TLX2_HUMAN (114-196): 1.57e-12: 67: 48.19
+	Dm
		985051 Q3KN55_DROME (591-1104): 8.35e-70: 250: 16.60		Q058W3_DROME (124-185): 7.37e-12: 65.9: 59.68
+	Hs
		678842 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXA7_HUMAN (14-196): 9.48e-34: 123: 21.28
+	Hs
		595612 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXA5_HUMAN (20-199): 2.3e-32: 120: 20.32
+	Hs
		446872 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXD4_HUMAN (3-210): 5.78e-32: 118: 20.95
+	Hs
		453058 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXB7_HUMAN (7-194): 3.91e-32: 118: 20.73
+	Hs
		678950 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXC8_HUMAN (2-192): 2.32e-30: 114: 21.65
+	Hs
		567802 ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09		HXB8_HUMAN (5-210): 4.48e-30: 113: 22.33
+	Hs
		166890 ANR28_HUMAN (263-705): 1.03e-30: 133: 9.87		HXA7_HUMAN (14-196): 9.48e-34: 123: 21.28
+	Hs
		257562 ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86		HXA5_HUMAN (20-199): 2.3e-32: 120: 20.32
+	Hs
		257549 ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86		HXD4_HUMAN (3-210): 5.78e-32: 118: 20.95
+	Hs
		257551 ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86		HXB7_HUMAN (7-194): 3.91e-32: 118: 20.73