Protein: AP2A1
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)

Gene: AP2A1
Organism: Mus musculus
Interactions: 33
UniProt ID: P17426

Gene Ontology (top 5):
GO:0006886 - intracellular protein transport
GO:0008021 - synaptic vesicle
GO:0009898 - cytoplasmic side of plasma membrane
GO:0010976 - positive regulation of neuron projection development
GO:0016192 - vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604461

CLH1
Clathrin heavy chain 1

1

9

Small-scale

0.618

High

604471

AP2B1
AP-2 complex subunit beta

1

15

Small-scale

0.618

High

604462

NEB2
Neurabin-2

2

9

High-throughput

0.584

High

604452

SNP25
Synaptosomal-associated protein 25

1

2

Small-scale

0.536

High

604453

TNIK
Traf2 and NCK-interacting protein kinase

1

3

High-throughput

0.536

High

604456

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

6

High-throughput

0.536

High

604459

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.536

High

604458

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

3

High-throughput

0.489

High

604463

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

3

High-throughput

0.489

High

604465

PEX5R
PEX5-related protein

1

3

High-throughput

0.489

High

266643

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

1

3

Small-scale

0.479

High

530700

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.479

High

604455

EGFR
Epidermal growth factor receptor

1

13

Small-scale

0.479

High

604468

ATG5
Autophagy protein 5

1

5

Small-scale

0.479

High

204985

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.458

High

604454

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

0

Small-scale

0.458

High

508952

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

16

High-throughput

0.457

High

569599

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.445

High

604449

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.445

High

604450

CAV3
Caveolin-3

1

2

High-throughput

0.445

High

604457

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.445

High

604460

DLG4
Disks large homolog 4

1

2

High-throughput

0.445

High

604466

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

19

Small-scale

0.445

High

604470

RAB32
Ras-related protein Rab-32

1

5

High-throughput

0.445

High

97559

E9PV60
WD repeat and FYVE domain containing 4

1

6

High-throughput

0.437

High

108441

G3X9H5
Huntingtin

1

7

High-throughput

0.437

High

542824

RARA
Retinoic acid receptor alpha

1

12

Small-scale

0.437

High

604451

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

4

High-throughput

0.437

High

604464

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

7

High-throughput

0.437

High

604467

EED
Polycomb protein EED

1

10

High-throughput

0.437

High

604469

FOXP3
Forkhead box protein P3

1

3

High-throughput

0.437

High

551375

A4
Amyloid-beta precursor protein

1

4

Small-scale

0.408

High

604448

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025