HitPredict

Interactor 1: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Interactor 2: KCTD3 (Q9Y597)
BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45)
Gene: KCTD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35271311, 34315543
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 815
+	Hs
		1252628 SNX27_HUMAN (1-541): 0: 625: 100.00		SHKB1_HUMAN (14-661): 0: 1005: 65.46
+	Hs
		1075479 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		KCTD3_HUMAN (1-815): 0: 1392: 100.00
+	Hs
		153961 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		KCTD3_HUMAN (1-815): 0: 1392: 100.00
+	Hs
		1132930 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		KCTD3_HUMAN (1-815): 0: 1392: 100.00
+	Hs
		1075432 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		SHKB1_HUMAN (14-661): 0: 1005: 65.46
+	Hs
		153935 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		SHKB1_HUMAN (14-661): 0: 1005: 65.46
+	Hs
		1132910 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		SHKB1_HUMAN (14-661): 0: 1005: 65.46
+	Hs
		1296929 SNX27_HUMAN (1-541): 0: 625: 100.00		KCTD5_HUMAN (3-185): 7.92e-44: 160: 25.48
+	Hs
		1057234 SNX27_HUMAN (1-541): 0: 625: 100.00		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		1235392 NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43		KCD17_HUMAN (18-180): 2.26e-36: 141: 32.62
+	Hs
		1075465 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		KCTD5_HUMAN (3-185): 7.92e-44: 160: 25.48
+	Hs
		153954 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		KCTD5_HUMAN (3-185): 7.92e-44: 160: 25.48
+	Hs
		1075459 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		BACD3_HUMAN (14-150): 1.67e-38: 147: 27.34
+	Hs
		1057222 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		1075429 NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78		KCD17_HUMAN (18-180): 2.26e-36: 141: 32.62
+	Hs
		153919 NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		1132926 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		KCTD5_HUMAN (3-185): 7.92e-44: 160: 25.48
+	Hs
		1057225 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		67909 PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23		KCTD2_HUMAN (11-185): 1.92e-38: 145: 28.36
+	Hs
		1132909 NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70		KCD17_HUMAN (18-180): 2.26e-36: 141: 32.62