Interactor 1: ECHA (Q8BMS1)
Trifunctional enzyme subunit alpha, mitochondrial (Monolysocardiolipin acyltransferase) (MLCL AT) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]
Gene: Hadha

Interactor 2: ECHB (Q99JY0)
Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]
Gene: Hadhb

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 3HCDH~Thiolase_N, 3HCDH_N~Thiolase_N, ECH_1~Thiolase_C, ECH_1~Thiolase_N
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006635 - fatty acid beta-oxidation
GO:0016507 - mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0042645 - mitochondrial nucleoid
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 763
Mm

1 475
+ Hs
+ Dm
+ Ec
+ Hs
+ Dm
+ Hs
+ At

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Last updated: 11Aug2025