Protein: THIK
3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase)

Gene: THIK, ACAA1
Organism: Homo sapiens
Interactions: 50
UniProt ID: P09110

Gene Ontology (top 5):
GO:0000038 - very long-chain fatty acid metabolic process
GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0003988 - acetyl-CoA C-acyltransferase activity
GO:0005576 - extracellular region
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

142268

PEX7
Peroxisomal targeting signal 2 receptor

3

11

High-throughput

0.667

High

479212

PEX39
Peroxisomal biogenesis factor 39

3

0

High-throughput

0.638

High

479222

TPPC9
Trafficking protein particle complex subunit 9

3

0

High-throughput

0.638

High

479231

CRYL1
Lambda-crystallin homolog

1

4

High-throughput

0.618

High

479202

PEX5
Peroxisomal targeting signal 1 receptor

2

2

High-throughput

0.611

High

479208

TFCP2
Alpha-globin transcription factor CP2

2

1

High-throughput

0.606

High

479225

FEM1A
Protein fem-1 homolog A

2

3

High-throughput

0.606

High

479199

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

479214

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

1

High-throughput

0.574

High

144225

ACACB
Acetyl-CoA carboxylase 2

1

2

High-throughput

0.536

High

479197

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

479206

HBB
Hemoglobin subunit beta

1

2

High-throughput

0.536

High

479207

HBA
Hemoglobin subunit alpha

1

2

High-throughput

0.536

High

479210

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

1

High-throughput

0.536

High

216611

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

479198

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

479219

ABI1
Abl interactor 1

1

0

High-throughput

0.513

High

479224

SORT
Sortilin

1

0

High-throughput

0.513

High

470813

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.489

High

479220

ARG39
Rho guanine nucleotide exchange factor 39

1

4

High-throughput

0.489

High

479221

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

479223

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

352872

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.479

High

395353

ESR1
Estrogen receptor

1

3

High-throughput

0.479

High

399926

CATA
Catalase

1

1

High-throughput

0.479

High

479200

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

479203

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

479209

CUL3
Cullin-3

1

5

High-throughput

0.479

High

479229

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

122461

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.458

High

479201

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.458

High

479204

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

479228

BMP2K
BMP-2-inducible protein kinase

1

3

Small-scale

0.451

High

479196

UD2B7
UDP-glucuronosyltransferase 2B7

1

1

Small-scale

0.445

High

479215

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.445

High

479216

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.445

High

479217

TXD11
Thioredoxin domain-containing protein 11

1

4

High-throughput

0.439

High

479213

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.437

High

479218

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

479227

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

479233

RM42
Large ribosomal subunit protein mL42

2

0

High-throughput

0.328

High

479195

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

2

0

High-throughput

0.318

High

479194

TFPT
TCF3 fusion partner

1

0

High-throughput

0.279

Low

479205

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

479226

SPXN
Spexin

1

0

High-throughput

0.279

Low

479230

TRM6
tRNA

1

0

High-throughput

0.279

Low

479232

WASC3
WASH complex subunit 3

1

0

High-throughput

0.279

Low

479211

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.269

Low

168177

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

Small-scale

0.261

Low

274963

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025